HPE DL345 Gen11 vs HPE DL345 Gen12
A specification-by-specification comparison of the HPE ProLiant DL345 Gen11 and the HPE ProLiant Compute DL345 Gen12, built from HPE’s own documents. None of the headline measures favour the DL345 Gen11; 5 favour the DL345 Gen12, and 21 processors appear in both lists.
Bottom line. DL345 Gen12 leads on virtualisation, databases and in-memory work, AI and acceleration, network throughput. Neither vendor publishes benchmarks for these machines, so every call here is made on what their documents state.
The measures that decide it
Each row is a figure both vendors publish. Bars show the split between the two; a badge marks the larger figure, which is not always the better buy — a shallower chassis or a lower power ceiling can matter more.
Which one, and why
Drawn from the measures above and each model’s own data sheet. Neither vendor publishes benchmark results for these servers, so nothing here claims one is “faster”.
Choose the DL345 Gen11 if…
- A 2U drive envelope behind one processor: 34 SFF, 20 LFF or 36 E3.S bays, because HPE adds mid-tray and rear cages to the front drive boxes.
Choose the DL345 Gen12 if…
- Cores, fully populated: 192 against 160 on the DL345 Gen11
- Memory ceiling: 6 TB against 3 TB on the DL345 Gen11
- Accelerators: Up to 6 against Up to 4 on the DL345 Gen11
- Up to 192 cores behind a single socket, with the 500 W EPYC 9965 and 9755 on HPE’s list.
Where each one pulls ahead
Calls made on documented capacity only — cores, memory, bays, accelerators and network options — with the figures behind each one shown.
Side by side, differences first
Everything both documents state, grouped. The default view hides rows where the two machines are identical.
Processors
Every processor each vendor lists for the model, from its own document.
| Specification | DL345 Gen11 | DL345 Gen12 |
|---|---|---|
| Processors listed | 40 | 23 |
| Most cores per processor | 160 | 192 |
| Highest processor TDP | 400 W | 500 W |
| Processor families | AMD EPYC 9005 · AMD EPYC 9004 | AMD EPYC 9005 |
Memory
| Specification | DL345 Gen11 | DL345 Gen12 |
|---|---|---|
| DIMM slots | 12 | 24 |
| Slots per processor | 12 | 24 |
| Memory types | RDIMM DDR5-6400 (5th Generation AMD EPYC) · RDIMM DDR5-4800 (4th Generation AMD EPYC) | RDIMM DDR5-6400 (HPE DDR5 Smart Memory, Registered, EC8) · RDIMM 3DS DDR5-6400 (256 GB Quad Rank x4) |
Storage
Bay counts are the maximum each document states, including rear and mid-chassis positions.
| Specification | DL345 Gen11 | DL345 Gen12 |
|---|---|---|
| Documented layouts | 18 | 8 |
| Boot devices | HPE NS204i-u Gen11 NVMe Hot Plug Boot Optimized Storage Device (2 x 480GB M.2 NVMe, hardware RAID1) · HPE NS204i-u v2 480GB NVMe Hot Plug Boot Optimized Storage Device · HPE NS204i-u v2 960GB NVMe Hot Plug Boot Optimized Storage Device + 3 more | HPE NS204i-u v2 480GB NVMe Hot Plug Boot Optimized Storage Device · HPE NS204i-u v2 960GB NVMe Hot Plug Boot Optimized Storage Device · HPE NS204i-u v2 960GB NVMe SED Hot Plug Boot Optimized Storage Device + 2 more |
| Storage controllers | 13 | 11 |
Accelerators & I/O
| Specification | DL345 Gen11 | DL345 Gen12 |
|---|---|---|
| Accelerators supported | Up to 4 | Up to 6 |
| Double-wide cards listed | 0 | 2 |
| Network cards listed | 25 | 35 |
Power & platform
| Specification | DL345 Gen11 | DL345 Gen12 |
|---|---|---|
| Power-supply options | 6 | 7 |
| Output range | 500–2,200 W | 800–3,200 W |
| Management | HPE iLO 6 | HPE iLO 7 |
| Chassis depthVendors measure depth differently — see each data sheet | 8SFF / 24SFF / EDSFF chassis: 64.6 cm (25.45 in) | 8LFF CTO: 65.61 cm / 25.83 in deep |
Processors, memory, bays and power
The same charts each data sheet carries, drawn to the same scale so the two ranges can be read against each other.
DL345 Gen11: processors by cores and TDP
DL345 Gen12: processors by cores and TDP
DL345 Gen11: memory with every slot filled
DL345 Gen12: memory with every slot filled
DL345 Gen11: drive bays
Front panel
36 × EDSFF NVMe at the front — 36 bays in total.
DL345 Gen12: drive bays
Front panel
8 × 2.5" SAS/SATA + NVMe at the front — 8 bays in total.
DL345 Gen11: power supplies
DL345 Gen12: power supplies
21 processors you can order in either
Both vendor documents list these parts, so a build can be matched across the two and the comparison comes down to the chassis: 19 more are exclusive to the DL345 Gen11 and 2 to the DL345 Gen12.
| Processor | Cores | TDP |
|---|---|---|
| AMD EPYC 9845 | 160 | 390 W |
| AMD EPYC 9825 | 144 | 390 W |
| AMD EPYC 9745 | 128 | 400 W |
| AMD EPYC 9645 | 96 | 320 W |
| AMD EPYC 9655P | 96 | 400 W |
| AMD EPYC 9565 | 72 | 400 W |
| AMD EPYC 9535 | 64 | 300 W |
| AMD EPYC 9575F | 64 | 400 W |
| AMD EPYC 9555P | 64 | 360 W |
| AMD EPYC 9475F | 48 | 400 W |
| AMD EPYC 9455P | 48 | 300 W |
| AMD EPYC 9365 | 36 | 300 W |
DL345 Gen11 vs DL345 Gen12, answered
Is the DL345 Gen11 or the DL345 Gen12 the faster server?
Neither document publishes benchmark results, so this page compares what they do state. The DL345 Gen11 lists 40 processors up to 160 cores at 400 W; the DL345 Gen12 lists 23 up to 192 cores at 500 W. Fully populated that is 160 cores against 192.
Which holds more memory?
The DL345 Gen11 has 12 DIMM slots and a stated ceiling of 3.0 TB. The DL345 Gen12 has 24 and 6.0 TB.
Which takes more drives?
DL345 Gen11: 36 bays across 18 documented layouts. DL345 Gen12: 36 across 8. Counts include rear and mid-chassis positions where the vendor documents them.
Can either take GPUs?
DL345 Gen11: up to 4 accelerators, 0 double-wide cards listed. DL345 Gen12: up to 6, 2 double-wide listed.
Do they share any processors?
Yes — 21 processors appear in both documents, including the AMD EPYC 9845. That makes a like-for-like build possible on either server.
Where these figures come from. DL345 Gen11: HPE ProLiant DL345 Gen11 QuickSpecs (Version 40 - August 3, 2026; footer a50004298enw V40 03-August-2026) (HPE document). DL345 Gen12: HPE ProLiant Compute DL345 Gen12 QuickSpecs (Version 12 - 03-Aug-2026; header prints Version 12 - August 3, 2026) (HPE document). Each claim on this page is derived from those documents, checked page by page on the two data sheets, and carries no pricing.
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