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Head-to-head · every figure from the vendor documents

HPE DL345 Gen11 vs HPE DL345 Gen12

A specification-by-specification comparison of the HPE ProLiant DL345 Gen11 and the HPE ProLiant Compute DL345 Gen12, built from HPE’s own documents. None of the headline measures favour the DL345 Gen11; 5 favour the DL345 Gen12, and 21 processors appear in both lists.

Bottom line. DL345 Gen12 leads on virtualisation, databases and in-memory work, AI and acceleration, network throughput. Neither vendor publishes benchmarks for these machines, so every call here is made on what their documents state.

HPE ProLiant DL345 Gen11 2U front with the HPE bezel over the drive cages, and the iLO service port and USB port on the right ear
HPE ProLiant
DL345 Gen11
2U Rack1 socket12 DIMMHPE iLO 6
VS
HPE ProLiant Compute DL345 Gen12 in the 8LFF chassis: eight LFF bays, two SFF bays and an optical drive, with the model badge on the right ear
HPE ProLiant
DL345 Gen12
2U Rack1 socket24 DIMMHPE iLO 7
01 — Scoreboard

The measures that decide it

Each row is a figure both vendors publish. Bars show the split between the two; a badge marks the larger figure, which is not always the better buy — a shallower chassis or a lower power ceiling can matter more.

1
Processor sockets
1
160
Cores, fully populated
Largest listed processor × its socket count
Higher192
3 TB
Memory ceiling
As each document states it
Higher6 TB
36
Drive bays
36
Up to 4
Accelerators
HigherUp to 6
2,200 W
Largest power supply
Higher3,200 W
2U Rack
Rack height
2U Rack
200 GbE class
Fastest network option
Higher400 GbE class
02 — Verdict

Which one, and why

Drawn from the measures above and each model’s own data sheet. Neither vendor publishes benchmark results for these servers, so nothing here claims one is “faster”.

Choose the DL345 Gen11 if…

  • A 2U drive envelope behind one processor: 34 SFF, 20 LFF or 36 E3.S bays, because HPE adds mid-tray and rear cages to the front drive boxes.

Choose the DL345 Gen12 if…

  • Cores, fully populated: 192 against 160 on the DL345 Gen11
  • Memory ceiling: 6 TB against 3 TB on the DL345 Gen11
  • Accelerators: Up to 6 against Up to 4 on the DL345 Gen11
  • Up to 192 cores behind a single socket, with the 500 W EPYC 9965 and 9755 on HPE’s list.
03 — By workload

Where each one pulls ahead

Calls made on documented capacity only — cores, memory, bays, accelerators and network options — with the figures behind each one shown.

VirtualisationDL345 Gen11: 160 cores with 3 TB. DL345 Gen12: 192 cores with 6 TB.DL345 Gen12
Databases & in-memoryMemory ceiling 3 TB against 6 TB, across 12 and 24 DIMM slots.DL345 Gen12
Storage density36 bays in 2U against 36 in 2U.Line ball
AI & acceleration4 accelerators against 6 in the vendor documents.DL345 Gen12
Network throughputFastest card listed: 200 GbE class against 400 GbE class.DL345 Gen12
04 — Specifications

Side by side, differences first

Everything both documents state, grouped. The default view hides rows where the two machines are identical.

Processors

Every processor each vendor lists for the model, from its own document.

SpecificationDL345 Gen11DL345 Gen12
Processors listed4023
Most cores per processor160192
Highest processor TDP400 W500 W
Processor familiesAMD EPYC 9005 · AMD EPYC 9004AMD EPYC 9005

Memory

SpecificationDL345 Gen11DL345 Gen12
DIMM slots1224
Slots per processor1224
Memory typesRDIMM DDR5-6400 (5th Generation AMD EPYC) · RDIMM DDR5-4800 (4th Generation AMD EPYC)RDIMM DDR5-6400 (HPE DDR5 Smart Memory, Registered, EC8) · RDIMM 3DS DDR5-6400 (256 GB Quad Rank x4)

Storage

Bay counts are the maximum each document states, including rear and mid-chassis positions.

SpecificationDL345 Gen11DL345 Gen12
Documented layouts188
Boot devicesHPE NS204i-u Gen11 NVMe Hot Plug Boot Optimized Storage Device (2 x 480GB M.2 NVMe, hardware RAID1) · HPE NS204i-u v2 480GB NVMe Hot Plug Boot Optimized Storage Device · HPE NS204i-u v2 960GB NVMe Hot Plug Boot Optimized Storage Device + 3 moreHPE NS204i-u v2 480GB NVMe Hot Plug Boot Optimized Storage Device · HPE NS204i-u v2 960GB NVMe Hot Plug Boot Optimized Storage Device · HPE NS204i-u v2 960GB NVMe SED Hot Plug Boot Optimized Storage Device + 2 more
Storage controllers1311

Accelerators & I/O

SpecificationDL345 Gen11DL345 Gen12
Accelerators supportedUp to 4Up to 6
Double-wide cards listed02
Network cards listed2535

Power & platform

SpecificationDL345 Gen11DL345 Gen12
Power-supply options67
Output range500–2,200 W800–3,200 W
ManagementHPE iLO 6HPE iLO 7
Chassis depthVendors measure depth differently — see each data sheet8SFF / 24SFF / EDSFF chassis: 64.6 cm (25.45 in)8LFF CTO: 65.61 cm / 25.83 in deep
05 — The data

Processors, memory, bays and power

The same charts each data sheet carries, drawn to the same scale so the two ranges can be read against each other.

DL345 Gen11: processors by cores and TDP

HPE ProLiant DL345 Gen11 processors081624324048566472808896104112120128136144152160100 W150 W200 W250 W300 W350 W400 WCores per processorAMD EPYC 9845 — 160 cores · 390 W · 2.1 GHz base · 320 MB cache · DDR5-6400AMD EPYC 9825 — 144 cores · 390 W · 2.2 GHz base · 384 MB cache · DDR5-6400AMD EPYC 9745 — 128 cores · 400 W · 2.4 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9655P — 96 cores · 400 W · 2.6 GHz base · 384 MB cache · DDR5-6400AMD EPYC 9645 — 96 cores · 320 W · 2.3 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9565 — 72 cores · 400 W · 3.15 GHz base · 384 MB cache · DDR5-6400AMD EPYC 9575F — 64 cores · 400 W · 3.3 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9555P — 64 cores · 360 W · 3.2 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9535 — 64 cores · 300 W · 2.4 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9475F — 48 cores · 400 W · 3.65 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9455P — 48 cores · 300 W · 3.15 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9365 — 36 cores · 300 W · 3.4 GHz base · 192 MB cache · DDR5-6400AMD EPYC 9375F — 32 cores · 320 W · 3.8 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9355P — 32 cores · 280 W · 3.55 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9335 — 32 cores · 210 W · 3 GHz base · 128 MB cache · DDR5-6400AMD EPYC 9275F — 24 cores · 320 W · 4.1 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9255 — 24 cores · 200 W · 3.25 GHz base · 128 MB cache · DDR5-6400AMD EPYC 9175F — 16 cores · 320 W · 4.2 GHz base · 512 MB cache · DDR5-6400AMD EPYC 9135 — 16 cores · 200 W · 3.65 GHz base · 64 MB cache · DDR5-6400AMD EPYC 9115 — 16 cores · 125 W · 2.6 GHz base · 64 MB cache · DDR5-6400AMD EPYC 9015 — 8 cores · 125 W · 3.6 GHz base · 64 MB cache · DDR5-6400AMD EPYC 9754 — 128 cores · 360 W · 2.25 GHz base · 256 MB cache · DDR5-4800AMD EPYC 9734 — 112 cores · 340 W · 2.2 GHz base · 256 MB cache · DDR5-4800AMD EPYC 9684X — 96 cores · 400 W · 2.55 GHz base · 1150 MB cache · DDR5-4800AMD EPYC 9654P — 96 cores · 360 W · 2.4 GHz base · 384 MB cache · DDR5-4800AMD EPYC 9634 — 84 cores · 290 W · 2.25 GHz base · 384 MB cache · DDR5-4800AMD EPYC 9554P — 64 cores · 360 W · 3.1 GHz base · 256 MB cache · DDR5-4800AMD EPYC 9534 — 64 cores · 280 W · 2.45 GHz base · 256 MB cache · DDR5-4800AMD EPYC 9474F — 48 cores · 360 W · 3.6 GHz base · 256 MB cache · DDR5-4800AMD EPYC 9454P — 48 cores · 290 W · 2.75 GHz base · 256 MB cache · DDR5-4800AMD EPYC 9374F — 32 cores · 320 W · 3.85 GHz base · 256 MB cache · DDR5-4800AMD EPYC 9384X — 32 cores · 320 W · 3.1 GHz base · 768 MB cache · DDR5-4800AMD EPYC 9354P — 32 cores · 280 W · 3.25 GHz base · 256 MB cache · DDR5-4800AMD EPYC 9334 — 32 cores · 210 W · 2.7 GHz base · 128 MB cache · DDR5-4800AMD EPYC 9274F — 24 cores · 320 W · 4.05 GHz base · 256 MB cache · DDR5-4800AMD EPYC 9254 — 24 cores · 200 W · 2.9 GHz base · 128 MB cache · DDR5-4800AMD EPYC 9224 — 24 cores · 200 W · 2.5 GHz base · 64 MB cache · DDR5-4800AMD EPYC 9174F — 16 cores · 320 W · 4.1 GHz base · 256 MB cache · DDR5-4800AMD EPYC 9184X — 16 cores · 320 W · 3.55 GHz base · 768 MB cache · DDR5-4800AMD EPYC 9124 — 16 cores · 200 W · 3 GHz base · 64 MB cache · DDR5-4800EPYC 9845160 cores · 2.4 W/core — top SKU and most efficient
AMD EPYC 9005 21AMD EPYC 9004 19Bubble size = L3 cache · hover a bubble for the full SKU

DL345 Gen12: processors by cores and TDP

HPE ProLiant Compute DL345 Gen12 processors081624324048566472808896104112120128136144152160168176184192100 W150 W200 W250 W300 W350 W400 W450 W500 WCores per processorAMD EPYC 9965 — 192 cores · 500 W · 2.25 GHz base · 384 MB cache · DDR5-6400AMD EPYC 9845 — 160 cores · 390 W · 2.1 GHz base · 320 MB cache · DDR5-6400AMD EPYC 9825 — 144 cores · 390 W · 2.2 GHz base · 384 MB cache · DDR5-6400AMD EPYC 9755 — 128 cores · 500 W · 2.7 GHz base · 512 MB cache · DDR5-6400AMD EPYC 9745 — 128 cores · 400 W · 2.4 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9655P — 96 cores · 400 W · 2.6 GHz base · 384 MB cache · DDR5-6400AMD EPYC 9645 — 96 cores · 320 W · 2.3 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9565 — 72 cores · 400 W · 3.15 GHz base · 384 MB cache · DDR5-6400AMD EPYC 9575F — 64 cores · 400 W · 3.3 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9555P — 64 cores · 360 W · 3.2 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9535 — 64 cores · 300 W · 2.4 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9475F — 48 cores · 400 W · 3.65 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9455P — 48 cores · 300 W · 3.15 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9365 — 36 cores · 300 W · 3.4 GHz base · 192 MB cache · DDR5-6400AMD EPYC 9375F — 32 cores · 320 W · 3.8 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9355P — 32 cores · 280 W · 3.55 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9335 — 32 cores · 210 W · 3 GHz base · 128 MB cache · DDR5-6400AMD EPYC 9275F — 24 cores · 320 W · 4.1 GHz base · 256 MB cache · DDR5-6400AMD EPYC 9255 — 24 cores · 200 W · 3.2 GHz base · 128 MB cache · DDR5-6400AMD EPYC 9175F — 16 cores · 320 W · 4.2 GHz base · 512 MB cache · DDR5-6400AMD EPYC 9135 — 16 cores · 200 W · 3.65 GHz base · 64 MB cache · DDR5-6400AMD EPYC 9115 — 16 cores · 125 W · 2.6 GHz base · 64 MB cache · DDR5-6400AMD EPYC 9015 — 8 cores · 125 W · 3.6 GHz base · 64 MB cache · DDR5-6400EPYC 9965192 cores — the top SKUEPYC 98452.4 W/core — most efficient
AMD EPYC 9005 23Bubble size = L3 cache · hover a bubble for the full SKU

DL345 Gen11: memory with every slot filled

16 GB192 GB32 GB384 GB64 GB768 GB96 GB1.1 TB128 GB1.5 TB256 GB3 TB12 slots · 12 per processor · each tick = one DIMM

DL345 Gen12: memory with every slot filled

32 GB768 GB64 GB1.5 TB96 GB2.3 TB128 GB3 TB256 GB6 TB24 slots · 24 per processor · each tick = one DIMM

DL345 Gen11: drive bays

Front panel

36 × EDSFF NVMe at the front — 36 bays in total.

SAS/SATANVMeSAS/SATA + NVMe

DL345 Gen12: drive bays

Front panel

8 × 2.5" SAS/SATA + NVMe at the front — 8 bays in total.

SAS/SATANVMeSAS/SATA + NVMe

DL345 Gen11: power supplies

05001000150020002500500 W Platinum — HPE 500W Flex Slot Platinum Hot Plug Low Halogen Power Supply Kit. 94% power efficiency. Rated steady-state 500W at 100 VAC / 240 VAC (240 VAC input for China only). BTU max 1979 (100 VAC) / 1911 (200 VAC) / 1965 (240 VAC, China).500Platinum800 W Platinum — HPE 800W Flex Slot Platinum Hot Plug Low Halogen Power Supply Kit. 94% power efficiency. BTU max 3207 (100 VAC) / 3071 (200 VAC) / 3112 (240 VAC, China).800Platinum1000 W Titanium — HPE 1000W Flex Slot Titanium Hot Plug (Low Halogen) Power Supply Kit. 96% power efficiency; named in the EU ErP Lot 9 compliant list.1000Titanium1600 W null — HPE 1600W Flex Slot -48VDC Hot Plug Power Supply Kit. Standard Features prose says 'Available in 94% Power Efficiency. 200-240VAC power input only.' No Platinum/Titanium label is printed. Requires the HPE 1600W -48VDC Power Cable Lug Kit (P36877-B21).1600DC1600 W Platinum — HPE 1600W Flex Slot Platinum Hot Plug Low Halogen Power Supply Kit. 94% power efficiency. High-line only: 200-240 VAC. BTU max 5918 (200 VAC) / 5884 (240 VAC, China).1600Platinum2200 W Titanium — HPE 1800W-2200W Flex Slot Titanium Hot Plug Power Supply Kit (rated 1800W at low line / 2200W at high line as printed in the SKU name; the document gives no separate efficiency percentage). Named in the EU ErP Lot 9 96%-efficient list.18002200TitaniumWatts · dashed line = output at 100–120 V low line
AC−48 V DC

DL345 Gen12: power supplies

0500100015002000250030003500800 W Platinum — HPE 800W M-CRPS Platinum Hot Plug Power Supply Kit. Explicitly excluded from the 96%-efficiency statement ('All of the above power supplies, except P73190-B21, are rated for 96% efficiency') and is NOT on the EU ErP Lot 9 compliant part-number list. Rated steady-state output 650W at 100-120 VAC / 800W at 200-240 VAC. BTU max 2458 (100 VAC) / 2919 (240 VAC).800Platinum1000 W Titanium — HPE 1000W M-CRPS Titanium Hot Plug Power Supply Kit; 96% efficiency; EU ErP Lot 9 compliant. Output 800W at 100-120 VAC / 1000W at 200-240 VAC (and 240 VDC China only). BTU max 3044 / 3680.1000Titanium1300 W null — HPE 1300W M-CRPS -48VDC Hot Plug Power Supply Kit. Requires HPE 1000-1300W -48VDC Power Lug Kit (P79845-B21). Listed only in the Core Options Power Supplies step, not in the Standard Features M-CRPS list.1300DC1500 W Titanium — HPE 1500W M-CRPS Titanium Hot Plug Power Supply Kit; 96% efficiency; EU ErP Lot 9 compliant. Output 1000W at 100 VAC / 1100W at 110-120 VAC / 1500W at 200-240 VAC. BTU max 3792 / 5560.1500Titanium2200 W null — HPE 2200W M-CRPS -48VDC Hot Plug Power Supply Kit. No efficiency rating is printed for the DC supplies. Requires HPE 2000-2200W -48VDC Power Lug Kit (P79839-B21). Listed only in the Core Options Power Supplies step, not in the Standard Features M-CRPS list, and not covered by the BTU/output tables.2200DC2400 W Titanium — HPE 2400W M-CRPS Titanium Hot Plug Power Supply Kit; 96% efficiency; EU ErP Lot 9 compliant. Steady-state 1200W at 100-127 VAC / 2400W at 200-240 VAC; peak 2400W at both line voltages. BTU max 4268 / 8532.2400Titanium3200 W Titanium — HPE 3200W M-CRPS Titanium Hot Plug Power Supply Kit; 96% efficiency; EU ErP Lot 9 compliant. Output 1600W at 100-127 VAC / 3200W at 200-240 VAC. BTU max 5142 / 11699.3200TitaniumWatts · dashed line = output at 100–120 V low line
AC−48 V DC
06 — Like for like

21 processors you can order in either

Both vendor documents list these parts, so a build can be matched across the two and the comparison comes down to the chassis: 19 more are exclusive to the DL345 Gen11 and 2 to the DL345 Gen12.

ProcessorCoresTDP
AMD EPYC 9845160390 W
AMD EPYC 9825144390 W
AMD EPYC 9745128400 W
AMD EPYC 964596320 W
AMD EPYC 9655P96400 W
AMD EPYC 956572400 W
AMD EPYC 953564300 W
AMD EPYC 9575F64400 W
AMD EPYC 9555P64360 W
AMD EPYC 9475F48400 W
AMD EPYC 9455P48300 W
AMD EPYC 936536300 W
07 — Questions

DL345 Gen11 vs DL345 Gen12, answered

Is the DL345 Gen11 or the DL345 Gen12 the faster server?

Neither document publishes benchmark results, so this page compares what they do state. The DL345 Gen11 lists 40 processors up to 160 cores at 400 W; the DL345 Gen12 lists 23 up to 192 cores at 500 W. Fully populated that is 160 cores against 192.

Which holds more memory?

The DL345 Gen11 has 12 DIMM slots and a stated ceiling of 3.0 TB. The DL345 Gen12 has 24 and 6.0 TB.

Which takes more drives?

DL345 Gen11: 36 bays across 18 documented layouts. DL345 Gen12: 36 across 8. Counts include rear and mid-chassis positions where the vendor documents them.

Can either take GPUs?

DL345 Gen11: up to 4 accelerators, 0 double-wide cards listed. DL345 Gen12: up to 6, 2 double-wide listed.

Do they share any processors?

Yes — 21 processors appear in both documents, including the AMD EPYC 9845. That makes a like-for-like build possible on either server.

Where these figures come from. DL345 Gen11: HPE ProLiant DL345 Gen11 QuickSpecs (Version 40 - August 3, 2026; footer a50004298enw V40 03-August-2026) (HPE document). DL345 Gen12: HPE ProLiant Compute DL345 Gen12 QuickSpecs (Version 12 - 03-Aug-2026; header prints Version 12 - August 3, 2026) (HPE document). Each claim on this page is derived from those documents, checked page by page on the two data sheets, and carries no pricing.

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