HPE DL380a Gen11 vs HPE DL380a Gen12
A specification-by-specification comparison of the HPE ProLiant DL380a Gen11 and the HPE ProLiant Compute DL380a Gen12, built from HPE’s own documents. 1 headline measure favours the DL380a Gen11, 5 favour the DL380a Gen12, and they share no processors.
Bottom line. DL380a Gen12 leads on virtualisation, databases and in-memory work, AI and acceleration. Neither vendor publishes benchmarks for these machines, so every call here is made on what their documents state.
The measures that decide it
Each row is a figure both vendors publish. Bars show the split between the two; a badge marks the larger figure, which is not always the better buy — a shallower chassis or a lower power ceiling can matter more.
Which one, and why
Drawn from the measures above and each model’s own data sheet. Neither vendor publishes benchmark results for these servers, so nothing here claims one is “faster”.
Choose the DL380a Gen11 if…
- Rack height: 2U Rack against 4U Rack on the DL380a Gen12
- Four double-wide or eight single-wide accelerators in a 2U chassis, with six NVIDIA and Intel cards in HPE’s GPU table spanning the 72 W L4 to the 400 W H100 NVL.
Choose the DL380a Gen12 if…
- Cores, fully populated: 288 against 128 on the DL380a Gen11
- Memory ceiling: 8 TB against 3 TB on the DL380a Gen11
- Drive bays: 16 against 8 on the DL380a Gen11
- Ten double-wide GPU positions in 4U, with the H200 NVL, RTX PRO 6000 Blackwell, RTX PRO 6000D, L40S, L20 and L4 in HPE’s accelerator list.
Where each one pulls ahead
Calls made on documented capacity only — cores, memory, bays, accelerators and network options — with the figures behind each one shown.
Side by side, differences first
Everything both documents state, grouped. The default view hides rows where the two machines are identical.
Processors
Every processor each vendor lists for the model, from its own document.
| Specification | DL380a Gen11 | DL380a Gen12 |
|---|---|---|
| Processors listed | 41 | 32 |
| Most cores per processor | 64 | 144 |
| Processor families | 4th Gen Xeon Scalable · 5th Gen Xeon Scalable | Xeon 6 E-core · Xeon 6 P-core |
Memory
| Specification | DL380a Gen11 | DL380a Gen12 |
|---|---|---|
| DIMM slots | 24 | 32 |
| Slots per processor | 12 | 16 |
| Largest module listed | 128 GB | 256 GB |
| Fastest rated speed | 5,600 MT/s | 6,400 MT/s |
| Memory types | RDIMM DDR5-4800 (HPE DDR5 Smart Memory, Registered) · RDIMM DDR5-5600 (HPE DDR5 Smart Memory, Registered) | RDIMM DDR5-6400 |
Storage
Bay counts are the maximum each document states, including rear and mid-chassis positions.
| Specification | DL380a Gen11 | DL380a Gen12 |
|---|---|---|
| Maximum bays | 8 | 16 |
| Boot devices | HPE NS204i-u Gen11 NVMe Hot Plug Boot Optimized Storage Device | HPE NS204i-u v2 960GB NVMe Hot Plug Boot Optimized Storage Device · HPE NS204i-u v2 960GB NVMe SED Hot Plug Boot Optimized Storage Device · HPE NS204i-u v2 480GB NVMe Hot Plug Boot Optimized Storage Device + 1 more |
| Storage controllers | 5 | 7 |
Accelerators & I/O
| Specification | DL380a Gen11 | DL380a Gen12 |
|---|---|---|
| Accelerators supported | Up to 8 | Up to 10 |
| PCIe network slots | 4 | 6 |
| Network cards listed | 32 | 36 |
Power & platform
| Specification | DL380a Gen11 | DL380a Gen12 |
|---|---|---|
| Power-supply options | 2 | 3 |
| Output range | 1,600–2,200 W | 2,400–3,200 W |
| Input types | AC | AC · 277 VAC / HVDC |
| Management | HPE iLO 6 | HPE iLO 7 |
| Chassis depthVendors measure depth differently — see each data sheet | 81.6 cm / 32.13 in deep (server) | 80.26 cm (31.60 in) deep |
Processors, memory, bays and power
The same charts each data sheet carries, drawn to the same scale so the two ranges can be read against each other.
DL380a Gen11: processors by cores and TDP
DL380a Gen12: processors by cores and TDP
DL380a Gen11: memory with every slot filled
DL380a Gen12: memory with every slot filled
DL380a Gen11: drive bays
Front panel
8 × EDSFF NVMe at the front — 8 bays in total.
DL380a Gen12: drive bays
Front panel
4 × 2.5" NVMe at the front — 4 bays in total.
DL380a Gen11: power supplies
DL380a Gen12: power supplies
DL380a Gen11 vs DL380a Gen12, answered
Is the DL380a Gen11 or the DL380a Gen12 the faster server?
Neither document publishes benchmark results, so this page compares what they do state. The DL380a Gen11 lists 41 processors up to 64 cores at 350 W; the DL380a Gen12 lists 32 up to 144 cores at 350 W. Fully populated that is 128 cores against 288.
Which holds more memory?
The DL380a Gen11 has 24 DIMM slots and a stated ceiling of 3.0 TB. The DL380a Gen12 has 32 and 8.0 TB.
Which takes more drives?
DL380a Gen11: 8 bays across 2 documented layouts. DL380a Gen12: 16 across 2. Counts include rear and mid-chassis positions where the vendor documents them.
Can either take GPUs?
DL380a Gen11: up to 8 accelerators, 0 double-wide cards listed. DL380a Gen12: up to 10, 0 double-wide listed.
Do they share any processors?
No. The two documents list different processors, so a like-for-like processor build is not possible across these two.
Where these figures come from. DL380a Gen11: HPE ProLiant DL380a Gen11 QuickSpecs (Version 34 - August 3, 2026) (HPE document). DL380a Gen12: HPE ProLiant Compute DL380a Gen12 QuickSpecs (Version 20 - 08-Sep-2026) (HPE document). Each claim on this page is derived from those documents, checked page by page on the two data sheets, and carries no pricing.
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