Technical data sheet · ProLiant Compute Gen12 · 4U dual-socket, GPU-accelerated

HPE ProLiant Compute DL380a Gen12Specifications, configurations & comparisons

The ProLiant Compute DL380a Gen12 is HPE’s 4U accelerator server for Intel Xeon 6: two processors, 32 DDR5 slots and a front bay for up to ten double-wide GPUs. Ordering it is a chain of dependencies — the GPU count sets the supply count and switchboard kits, and the storage cabling decides how many rear slots survive — and this data sheet maps those rules from the QuickSpecs.

4U Rack2 socketsXeon 6 E-coreXeon 6 P-coreHPE iLO 7

10double-wide GPUs4U · 0, 1, 2, 4, 8 or 10 allowed

144cores per processorXeon 6 E-core 6766E / 6780E

8TBDDR5 maximum32 × 256 GB · 5200 MT/s at 2 DPC

16E3.S NVMe baysHPE table figure · cage kit max is 8

8M-CRPS suppliesfor 8 or 10 double-wide GPUs

3,200Wlargest PSUM-CRPS Titanium · C19 cords

Configure a DL380a Gen12 →Get a UK quote

Every figure checked against the HPE ProLiant Compute DL380a Gen12 QuickSpecs (Version 20 - 08-Sep-2026)

Image: Hewlett Packard Enterprise

Form factor: 4U Rack · 2 sockets
Processors: Xeon 6 E-core · Xeon 6 P-core
Memory: 32 × DDR5 RDIMM · up to 8.0 TB
Drive bays: Up to 16 · 2 drive-cage kits
Expansion: 6 × PCIe · 2 × OCP 3.0
GPUs: Up to 10 · 6 listed
Boot: NS204i · 4 boot options
Management: HPE iLO 7

01 — Overview

The DL380a Gen12 at a glance

Our read of HPE’s documentation: where the DL380a Gen12 is strong, and the limits worth knowing before you spec one.

Strengths

Ten double-wide GPU positions in 4U, with the H200 NVL, RTX PRO 6000 Blackwell, RTX PRO 6000D, L40S, L20 and L4 in HPE’s accelerator list.
Xeon 6 in both core types — six E-core models spanning 64–144 cores and 26 P-core models spanning 8–86 — all rated for DDR5-6400 apart from the 5600 MT/s 6710E and 6746E.
H200 NVL cards can be linked with HPE-listed 2-way or 4-way NVLink bridges in every layout except the ten-GPU 10DW configuration.
Memory reaches 8 TB with 256 GB 3DS RDIMMs, and a 4 TB build at one DIMM per channel keeps the full 6400 MT/s.
Two OCP 3.0 slots, six rear PCIe 5.0 x16 positions and a front-NIC mode that takes four networking cards at the front of the chassis.

Watch-outs

Supply count follows GPU count: five M-CRPS units (two for the system board, three for GPUs) with two or four double-wide GPUs, and eight with eight or ten.
Storage is NVMe-only and small — four or eight U.3, or four, eight or (by HPE’s storage table) sixteen E3.S — and the eight-drive rear direct-attach cabling leaves just two rear PCIe slots.
The iLO 6 CTO model (P74461-B21) cannot move to iLO 7 and rules out P-core processors, the RTX PRO 6000 and a list of NICs, controllers and HBAs.
HPE ties the Xeon 6776P to AI-host use: its warranty is void if the processor is used for general compute.
The ten-GPU layout drops NVLink bridge support and needs the front fan module and front panel kits; CPU liquid cooling cannot be combined with it.

Processors32 SKUs

Cores / CPU8–144

DIMM slots32

Drive-cage kits2

Max bays16

GPUsup to 10

PSU options3 · to 3,200 W

02 — Processors

32 supported processors, mapped

HPE’s feature table lists 32 Xeon 6 processors for the DL380a Gen12 — six 6700E-series E-core parts and 26 P-core parts from the 6500 and 6700 series — and 31 of them have option kits in the ordering steps. They run from 8 to 144 cores and 150 W to 350 W. Both sockets take the same model; there is no single-processor build.

Processor landscape — cores × TDP

32 SKUs · 2 families

Xeon 6 E-core 6Xeon 6 P-core 26Bubble size = L3 cache · hover a bubble for the full SKU

Processor explorer

filter · sort · compare

Sort

Processor	Cores / threads	Base	L3 cache	TDP	W / core	Memory
Intel Xeon 6780E	144	2.2 GHz	108 MB	330 W	2.3	DDR5-6400
Intel Xeon 6766E	144	1.9 GHz	108 MB	250 W	1.7	DDR5-6400
Intel Xeon 6756E	128	1.8 GHz	96 MB	225 W	1.8	DDR5-6400
Intel Xeon 6746E	112	2 GHz	96 MB	250 W	2.2	DDR5-5600
Intel Xeon 6740E	96	2.4 GHz	96 MB	250 W	2.6	DDR5-6400
Intel Xeon 6787P	86	2 GHz	336 MB	350 W	4.1	DDR5-6400
Intel Xeon 6788P	86	2 GHz	336 MB	350 W	4.1	DDR5-6400
Intel Xeon 6710E	64	2.4 GHz	96 MB	205 W	3.2	DDR5-5600
Intel Xeon 6767P	64	2.4 GHz	336 MB	350 W	5.5	DDR5-6400
Intel Xeon 6776P	64	2.3 GHz	336 MB	350 W	5.5	DDR5-6400
Intel Xeon 6760P	64	2.2 GHz	320 MB	330 W	5.2	DDR5-6400
Intel Xeon 6768P	64	2.4 GHz	336 MB	330 W	5.2	DDR5-6400
Intel Xeon 6747P	48	2.7 GHz	288 MB	330 W	6.9	DDR5-6400
Intel Xeon 6748P	48	2.5 GHz	192 MB	300 W	6.3	DDR5-6400
Intel Xeon 6740P	48	2.1 GHz	288 MB	270 W	5.6	DDR5-6400
Intel Xeon 6736P	36	2 GHz	144 MB	205 W	5.7	DDR5-6400
Intel Xeon 6732P	32	3.8 GHz	144 MB	350 W	10.9	DDR5-6400
Intel Xeon 6745P	32	3.1 GHz	336 MB	300 W	9.4	DDR5-6400
Intel Xeon 6737P	32	2.9 GHz	144 MB	270 W	8.4	DDR5-6400
Intel Xeon 6738P	32	2.9 GHz	144 MB	270 W	8.4	DDR5-6400
Intel Xeon 6730P	32	2.5 GHz	288 MB	250 W	7.8	DDR5-6400
Intel Xeon 6530P	32	2.3 GHz	144 MB	225 W	7.0	DDR5-6400
Intel Xeon 6527P	24	3 GHz	144 MB	255 W	10.6	DDR5-6400
Intel Xeon 6520P	24	2.4 GHz	144 MB	210 W	8.8	DDR5-6400
Intel Xeon 6728P	24	2.7 GHz	144 MB	210 W	8.8	DDR5-6400
Intel Xeon 6725P	16	3.7 GHz	192 MB	235 W	14.7	DDR5-6400
Intel Xeon 6724P	16	3.6 GHz	72 MB	210 W	13.1	DDR5-6400
Intel Xeon 6517P	16	3.2 GHz	72 MB	190 W	11.9	DDR5-6400
Intel Xeon 6515P	16	2.3 GHz	72 MB	150 W	9.4	DDR5-6400
Intel Xeon 6505P	12	2.2 GHz	48 MB	150 W	12.5	DDR5-6400
Intel Xeon 6714P	8	4 GHz	48 MB	165 W	20.6	DDR5-6400
Intel Xeon 6507P	8	3.5 GHz	48 MB	150 W	18.8	DDR5-6400

The 12-core 6505P appears only in the feature table, with no option kit to order.
The 8-core 6714P is shown at 195 W in the feature table but at 165 W in its option-kit name.
P-core processors are not available on the iLO 6 CTO model (P74461-B21), which leaves that model the six E-core parts.
The 6505P, 6507P, 6515P and 6517P have three UPI links and every other processor four; HPE’s table gives no link speed.
An optional CPU direct liquid cooling kit (P82520-B21) holds two cold plates and a quick-disconnect module, needs the 55 cm tube set (P62042-B21) and occupies rear PCIe slot 1.

03 — Memory

32 DIMM slots, 16 per processor

The board carries 32 DDR5 RDIMM slots — 16 per processor on eight channels, up to two DIMMs each. HPE rates its DDR5-6400 kits for 6400 MT/s with a lone DIMM per channel, dropping to 5200 MT/s once a second shares it, so the 8 TB maximum (32 × 256 GB) runs at 5200 MT/s and the 4 TB one-per-channel build at 6400 MT/s.

Capacity with every slot filled

by DIMM size

Operating speed

per HPE memory tables

Processor	1 DIMM / channel	2 DIMMs / channel
Intel Xeon 6 (E-core and P-core)	6400 MT/s*	5200 MT/s

* The processor caps the speed: HPE lists the 6710E and 6746E at 5600 MT/s and every other processor at 6400 MT/s.
Per-processor DIMM counts are 1, 2, 4, 8 or 16 with E-core parts and 1, 2, 4, 8, 12 or 16 with P-core parts; the ordering step instead gives system totals of 4, 8, 16 or 32 (E-core) and 4, 8, 16, 24 or 32 (P-core), which leaves out a single DIMM per socket.
The 16 GB DIMM is limited to quantities of 4, 8 or 16 and is not supported with E-core processors.
HPE recommends system memory of twice the GPU memory: eight 141 GB H200 NVL cards (1,128 GB) point to 2,256 GB of RDIMM.
Ranks cannot be mixed, x4 and x8 DIMMs cannot share a channel or socket, and every DIMM on a socket runs at one speed.

04 — Storage

2 drive-cage kits, up to 16 bays

The single front drive bay takes four-bay cages of one kind — 4SFF x4 U.3 NVMe or 4EDSFF — and one 4SFF cage is the shipping default. Only NVMe drives are offered, with no SAS, SATA or LFF option. HPE’s maximum-storage table quotes 122.88 TB on eight 15.36 TB U.3 drives and 245.76 TB on sixteen 15.36 TB E3.S drives.

Headline layouts

front panel view

Front panel

One 4SFF FIO cage (P74710-B21) with the 4NVMe Direct Attach Cable Kit (P74702-B21). That cable limits the OCPA cable kit to one and rules out the OCPB kit, and HPE’s OCP-adapter notes exclude OCP cards with it altogether.

SAS/SATANVMeSAS/SATA + NVMe

Controllers & boot

HPE NS204i-u v2 960GB NVMe Hot Plug Boot Optimized Storage Device — Boot. Configured in front chassis slot; does not occupy PCIe slots; requires HPE DL380a Gen12 NS204i-u Front Cage Kit (P75284-B21)
HPE NS204i-u v2 960GB NVMe SED Hot Plug Boot Optimized Storage Device — Boot. Self-encrypting; configured in front chassis slot; requires Front Cage Kit (P75284-B21)
HPE NS204i-u v2 480GB NVMe Hot Plug Boot Optimized Storage Device — Boot. Configured in front chassis slot; requires Front Cage Kit (P75284-B21)
Intel Virtual RAID on CPU Premium FIO Software for HPE — Software RAID. Listed under 'Hybrid RAID Controllers'. Intel VROC is the standard (embedded) storage controller on the CTO server; supports up to 8 direct-attach NVMe bays; RAID 0/1/5/10 depending on licensing; off by default and requires licensing. Only this Premium FIO licence is listed (no RAID1-only or E-RTU SKU).
HPE MR416i-p Gen11 x16 Lanes 8GB Cache PCI SPDM Plug-in Storage Controller — RAID, 8GB cache. Tri-Mode, PCIe plug-in; requires HPE DL380a Gen12 NVMe to Tri-Mode PCIe FIO Cable Kit (P76700-B21); battery or hybrid capacitor required; NOT supported on P74461-B21
HPE MR416i-o Gen11 x16 Lanes 8GB Cache OCP SPDM Storage Controller — RAID, 8GB cache. Tri-Mode, OCP form factor; requires HPE DL380a Gen12 NVMe to Tri-Mode OCP FIO Cable Kit (P76702-B21); battery or hybrid capacitor required; NOT supported on P74461-B21
HPE MR932i-p x32 Lanes PCIe Gen5 SPDM Plug-in Storage Controller — RAID. Listed under HPE Tri-Mode Controllers; cache size not printed. Qty 1 requires Qty 1 MR932i-p FIO Cable Kit (P80572-B21) + Qty 1 4EDSFF cage; Qty 2 requires Qty 2 P80572-B21 + Qty 4 4EDSFF cages. P80572-B21 only with P76706-B21 CTO server.
HPE NS204i-u v2 960GB NVMe Hot Plug Boot Optimized Storage Device (P81160-B21) — boot
HPE NS204i-u v2 960GB NVMe SED Hot Plug Boot Optimized Storage Device (P81162-B21) — boot
HPE NS204i-u v2 480GB NVMe Hot Plug Boot Optimized Storage Device (P78279-B21) — boot
HPE DL380a Gen12 NS204i-u Front Cage Kit (P75284-B21) — boot

Tri-mode controllers are the MR416i-p, MR416i-o and MR932i-p, and models cannot be mixed. HPE’s shared note fixes the count at two, while the MR932i-p note also describes a one-controller build with a single 4EDSFF cage.
The MR416i-p and MR416i-o need two 4SFF cages and the NVMe-to-tri-mode cable kits, which HPE offers only for the iLO 7 CTO model (P76706-B21); every controller needs a battery or hybrid capacitor.
Intel VROC runs up to eight direct-attached NVMe drives; it is off by default and licensed through the Premium FIO kit (R7J57A).
The NS204i-u v2 boot device (480 GB, 960 GB or 960 GB SED) sits in a front chassis slot with the front cage kit P75284-B21 and takes no PCIe slot.
EDSFF drives fit only the 4EDSFF cage and SFF drives only the 4SFF cage, and the two cage types cannot be mixed.

Every documented drive-cage kit

2 with drive bays

2.5-inch3.5-inchEDSFF (E1.S / E3.S)

05 — Accelerators & I/O

GPUs, PCIe and networking

The front bay holds up to ten double-wide GPUs, in allowed counts of 0, 1, 2, 4, 8 and 10. HPE lists six accelerators — RTX PRO 6000 Blackwell Server Edition 96 GB, RTX PRO 6000D 84 GB, H200 NVL 141 GB, L40S 48 GB, L20 48 GB and L4 24 GB — but prints no per-card TDP or width. Models cannot be mixed, the RTX PRO 6000 stops at eight, and each 16-pin GPU cable kit feeds two double-wide cards. Up to 10 double-wide GPUs (8 for RTX PRO 6000) · H200 NVL 2-way or 4-way NVLink bridges outside the 10-GPU layout

NVIDIA RTX PRO 6000 Blackwell Server Edition 96GB PCIe Accelerator for HPE

96GB · up to 8

NVIDIA RTX PRO 6000D 84GB PCIe Accelerator for HPE

84GB

NVIDIA H200 NVL 141GB PCIe Accelerator for HPE

141GB

NVIDIA L40S 48GB PCIe Accelerator

48GB

NVIDIA L20 48GB PCIe GPU Accelerator for HPE

48GB

NVIDIA L4 24GB PCIe Accelerator for HPE

24GB

I/O topology

2 sockets

Six rear PCIe 5.0 x16 full-height, half-length slots sit on two risers — slots 1–3 on the primary riser, wired to processor 2, and slots 4–6 on the secondary riser, wired to processor 1. Only slots 3 and 6 are live by default; the others depend on cable and riser kits that interact with the GPU layout and the storage cabling.

Network adapters HPE lists

36 options

Adapter	Ports	Form
Broadcom BCM57414 Ethernet 10/25Gb 2-port SFP28 Adapter for HPE	2 × 10/25GbE	PCIe
Broadcom BCM57504 Ethernet 10/25Gb 4-port SFP28 Adapter for HPE	4 × 10/25GbE	PCIe
Broadcom BCM5719 Ethernet 1Gb 4-port BASE-T Adapter for HPE	4 × 1GbE	PCIe
Broadcom BCM57416 Ethernet 10Gb 2-port BASE-T Adapter for HPE	2 × 10GbE	PCIe
Broadcom BCM57412 Ethernet 10Gb 2-port SFP+ Adapter for HPE	2 × 10GbE	PCIe
Broadcom BCM57608 Ethernet 100Gb 2-port QSFP112 Adapter for HPE	2 × 100GbE	PCIe
Intel E610-IT4 Ethernet 1Gb 4-port BASE-T OCP3 Adapter for HPE	4 × 1GbE	OCP 3.0
Intel E810-XXVDA2 Ethernet 10/25Gb 2-port SFP28 Adapter for HPE	2 × 10/25GbE	PCIe
Intel E810-XXVDA4 Ethernet 10/25Gb 4-port SFP28 Adapter for HPE	4 × 10/25GbE	PCIe
Intel E810-CQDA2 Ethernet 100Gb 2-port QSFP28 Adapter for HPE	2 × 100GbE	PCIe
Mellanox MCX631102AS-ADAT Ethernet 10/25Gb 2-port SFP28 Adapter for HPE	2 × 10/25GbE	PCIe
Mellanox MCX623106AS-CDAT Ethernet 100Gb 2-port QSFP56 Adapter for HPE	2 × 100GbE	PCIe
Broadcom BCM57414 Ethernet 10/25Gb 2-port SFP28 OCP3 Adapter for HPE	2 × 10/25GbE	OCP 3.0
Broadcom BCM57504 Ethernet 10/25Gb 4-port SFP28 OCP3 Adapter for HPE	4 × 10/25GbE	OCP 3.0
Broadcom BCM5719 Ethernet 1Gb 4-port BASE-T OCP3 Adapter for HPE	4 × 1GbE	OCP 3.0
Broadcom BCM57412 Ethernet 10Gb 2-port SFP+ OCP3 Adapter for HPE	2 × 10GbE	OCP 3.0
Broadcom BCM57416 Ethernet 10Gb 2-port BASE-T OCP3 Adapter for HPE	2 × 10GbE	OCP 3.0
Broadcom BCM57608 Ethernet 100Gb 2-port QSFP112 OCP3 Adapter for HPE	2 × 100GbE	OCP 3.0
Intel E810-XXVDA2 Ethernet 10/25Gb 2-port SFP28 OCP3 Adapter for HPE	2 × 10/25GbE	OCP 3.0
Intel E810-XXVDA4 Ethernet 10/25Gb 4-port SFP28 OCP3 Adapter for HPE	4 × 10/25GbE	OCP 3.0
Intel E810-CQDA2 Ethernet 100Gb 2-port QSFP28 OCP3 Adapter for HPE	2 × 100GbE	OCP 3.0
Mellanox MCX631432AS-ADAI Ethernet 10/25Gb 2-port SFP28 OCP3 Adapter for HPE	2 × 10/25GbE	OCP 3.0
HPE Data Processing Unit InfiniBand NDR200/Ethernet 200Gb 2-port QSFP112 FHHL B3220 Adapter	2 × InfiniBand NDR200 / 200GbE	PCIe
HPE Data Processing Unit InfiniBand NDR/Ethernet 400Gb 1-port QSFP112 HHHL B3140H Adapter	1 × InfiniBand NDR / 400GbE	PCIe
HPE InfiniBand NDR200/Ethernet 200Gb 1-port OSFP PCIe5 x16 MCX75310AAS-HEAT Generic Adapter	1 × InfiniBand NDR200 / 200GbE	PCIe
HPE InfiniBand NDR/Ethernet 400Gb 1-port OSFP PCIe5 x16 MCX75310AAS-NEAT Generic Adapter	1 × InfiniBand NDR / 400GbE	PCIe
HPE InfiniBand NDR/Ethernet 400Gb 1-port QSFP112 PCIe5 x16 MCX715105AS-WEAT Adapter	1 × InfiniBand NDR / 400GbE	PCIe
HPE InfiniBand XDR/Ethernet 2x400GbE 1-port OSFP PCIe6 x16 HHHL CX8 Crypto Adapter	1 × InfiniBand XDR / 2x400GbE	PCIe
HPE InfiniBand XDR400/Ethernet 400GbE 2-port QSFP112 PCIe6 x16 HHHL CX8 Crypto Adapter	2 × InfiniBand XDR400 / 400GbE	PCIe
HPE InfiniBand XDR PCIe Gen6 x16 Multi Host/Socket Direct Auxiliary Card with 250mm MCIO Cable Kit	× InfiniBand XDR	PCIe
HPE SN1620E 32Gb 2p FC SecureHBA	2 × 32Gb Fibre Channel	PCIe
HPE SN1720E 64Gb 2p FC SecureHBA	2 × 64Gb Fibre Channel	PCIe
HPE SN1610Q 32Gb 1-port Fibre Channel Host Bus Adapter	1 × 32Gb Fibre Channel	PCIe
HPE SN1610Q 32Gb 2-port Fibre Channel Host Bus Adapter	2 × 32Gb Fibre Channel	PCIe
HPE SN1700Q 64Gb 1-port Fibre Channel Host Bus Adapter	1 × 64Gb Fibre Channel	PCIe
HPE SN1700Q 64Gb 2-port Fibre Channel Host Bus Adapter	2 × 64Gb Fibre Channel	PCIe

Slot 4 is unavailable in the four- and eight-double-wide configurations.
HPE describes slot 1 two ways: usable only with the 4EDSFF Direct Attach Cable for NVIDIA (P74716-B21) and not with SFF NVMe drives, yet also enabled by the Rear PCIe Slot1/4 cable kit (P76698-B21) and the 5-slot kit. The CPU liquid-cooling kit occupies it.
The PCIe Rear FIO Kit (P74690-B21) turns on slots 2 and 5 for non-GPU cards — four usable slots in all, or five with the P74716-B21 cable.
OCP adapters use no PCIe slot; one card needs the OCPB kit or two OCPA kits, and two cards need both.
There is no embedded LAN. One DPU (BlueField B3220 or B3140H) is allowed per server and needs the 5-slot kit.
Fibre Channel HBAs can only be ordered on the iLO 7 CTO model (P76706-B21).

06 — Power & cooling

3 power supplies, 2,400–3,200 W

Supplies are HPE M-CRPS hot-plug units: 2400 W and 3200 W Titanium for 200–240 VAC, and a 2800 W Titanium unit for 277 VAC. Two or four double-wide GPUs need five supplies — two for the system board and three for the GPUs — and eight or ten need eight. Our configurator link shows two, so the documented count is set on the quote.

AC277 VAC / HVDC

H200 NVL and RTX PRO 6000 builds require the 2400 W or 3200 W supplies, which take C19/C19-C20 cords only; the same notes mention an H100 NVL that is not in the option list.
Supply models cannot be mixed in one server.
A server first built with fewer than eight GPUs can be field-upgraded to eight with the GPU Upgrade Kit (P81677-B21), which brings power cables and four PCIe switchboards; a five-supply server then needs three more of the same capacity.
Per-supply heat output tops out at 8572 BTU/hr for the 2400 W unit (200 VAC) and 11713 BTU/hr for the 3200 W unit (220 VAC); the table also lists a 1500 W supply that is not an option here.
On the iLO 6 CTO model more than five supplies calls for a PDB kit; the iLO 7 model needs none.
Cooling is four hot-plug fan assemblies, each one dual-rotor 92 mm fan and two single-rotor 40 mm fans; a failed fan, or inlet air warmer than 30 °C, can cost performance.

07 — Management, security & OS

Run it, secure it, choose the OS

Management

HPE iLO 7 (ROM ID U72) on the 8DW/16SW CTO model P76706-B21
HPE iLO 6 (ROM ID U70) on the 8DW CTO model P74461-B21 — not upgradable to iLO 7
iLO Standard with Intelligent Provisioning embedded; iLO Advanced, Premium Security Edition and OneView Advanced licensed
Three-year HPE Compute Ops Management subscription added by default
iLO RESTful API (Redfish), Active Health System and Smart Update Manager

Security

iLO-managed and UEFI-managed encryption with self-encrypting drive support
One-button secure erase to NIST SP 800-88
FIPS 140-3, NIST SP 800-53 and NIST SP 800-171 compliance
Embedded TPM 2.0; UEFI Class 3, UEFI mode only
System maintenance switch, USB security, bezel lock and chassis intrusion detection
HPE Trusted Supply Chain option

Operating systems

Operating-system and hypervisor certification sits in HPE’s Servers Support & Certification Matrices; the QuickSpecs list no versions
TPM 2.0, NVMe boot and HTTP/HTTPS boot require UEFI boot mode

08 — Compare

How the DL380a Gen12 compares with its family

The bars compare the DL380a Gen12 with the HPE models nearest to it in our spec set — the 2U DL380a Gen11, the DL380 Gen12, the DL384 Gen12, the XD685 and the DL580 Gen12 — using each model’s verified spec file.

This modelSiblings and successorEach value from that model’s own verified spec file · bars scale per column

DL380a Gen11 data sheet DL380 Gen12 data sheet DL384 Gen12 data sheet XD685 data sheet DL580 Gen12 data sheet Dell PowerEdge XE7740 data sheet Dell PowerEdge XE7745 data sheet Lenovo ThinkSystem SR675 V3 data sheet

09 — Use cases

Four builds that suit the DL380a Gen12

Four DL380a Gen12 builds from options our configurator permits on this model. The link opens with one drive cage and two supplies; the lines give HPE’s real counts — five or eight supplies, and any second cage — which we set on the quote. HPE writes its supply and switchboard counts for double-wide GPUs but prints no card widths, so each count is confirmed build by build.

LLM inference

Eight H200 NVL with NVLink

Eight 141 GB H200 NVL cards hold 1,128 GB of GPU memory, and HPE lists 2-way and 4-way NVLink bridges for this card. Sixteen 256 GB 3DS RDIMMs give 4 TB at one DIMM per channel — more than the 2,256 GB HPE’s twice-GPU-memory guideline asks for — behind two 64-core Xeon 6767P processors.

2 × Xeon 6767P — 64 cores @ 2.4 GHz, 350 W each
8 × NVIDIA H200 NVL 141 GB · NVLink bridges added on the quote
16 × 256 GB DDR5-6400 3DS RDIMM — 4 TB at one DIMM per channel
4 × 30.72 TB E3.S NVMe in one 4EDSFF cage
NS204i-u v2 boot device in the front cage
HPE InfiniBand XDR / 2 × 400 GbE 1-port OSFP adapter
8 × 3200 W M-CRPS Titanium — HPE’s count for eight double-wide GPUs (set on the quote)
Red Hat Enterprise Linux 9 (3-year)
HPE Tech Care Critical

Eight double-wide GPUs need two Switchboard FIO Enablement kits (P74714-B21), and the H200 NVL requires the 2400 W or 3200 W supplies. NVLink bridges work only with the H200 NVL and not in the ten-GPU layout. Rear slot 4 is unavailable with eight double-wide GPUs.

Open this build in the configurator →

AI & visual computing

Eight RTX PRO 6000 Blackwell

Eight 96 GB RTX PRO 6000 Blackwell cards — the most HPE allows of this model — give 768 GB of GPU memory for inference, rendering or simulation. Two 64-core Xeon 6776P processors, which HPE sells for AI-host duty, sit beside 32 × 64 GB of DDR5 for 2 TB.

2 × Xeon 6776P — 64 cores @ 2.3 GHz, 350 W each
8 × NVIDIA RTX PRO 6000 Blackwell Server Edition 96 GB
32 × 64 GB DDR5-6400 RDIMM — 2 TB, two per channel (5200 MT/s)
4 × 7.68 TB U.3 NVMe in the default 4SFF cage, direct-attached
NS204i-u v2 boot device in the front cage
HPE InfiniBand NDR200 / 200 GbE 1-port OSFP PCIe 5.0 x16
8 × 2400 W M-CRPS Titanium — HPE’s count for eight double-wide GPUs (set on the quote)
SUSE Linux Enterprise Server 15
HPE Tech Care Essential

Eight RTX PRO 6000 cards need the Front Chassis Fan Module Kit (P79656-B21) and Front Panel Kit (P79660-B21), are not supported in the 8DW NIC configuration and are not offered on the iLO 6 CTO model. The default single-cage cabling rules out OCP cards, so networking is a PCIe adapter. HPE voids the 6776P warranty for general-compute use.

Open this build in the configurator →

Inference at density

Ten L40S in the 10DW layout

The 10DW configuration fills every front GPU position: ten 48 GB L40S cards, 480 GB of GPU memory in all, for many concurrent inference or graphics sessions. Sixteen 64 GB RDIMMs give 1 TB — a little over twice the GPU memory — on 32-core Xeon 6737P processors.

2 × Xeon 6737P — 32 cores @ 2.9 GHz, 270 W each
10 × NVIDIA L40S 48 GB (10DW FIO configuration)
16 × 64 GB DDR5-6400 RDIMM — 1 TB, one per channel
4 × 3.84 TB U.3 NVMe in the default 4SFF cage
NS204i-u v2 boot device in the front cage
Broadcom BCM57608 2 × 100 GbE QSFP112 PCIe
8 × 2400 W M-CRPS Titanium — HPE’s count for ten double-wide GPUs (set on the quote)
Red Hat Enterprise Linux 9

The 10DW configuration is not offered on the iLO 6 CTO model; it pairs with the 10 Double Wide captive riser kit and needs the Front Chassis Fan Module and Front Panel kits. It supports no NVLink bridges, cannot be combined with CPU liquid cooling, and with the 5-slot cable kit leaves rear slots 1, 3 and 6 for non-GPU cards. HPE sets no L40S-specific count beyond its general 0/1/2/4/8/10 rule and prints no card widths, so the ten-card fit is confirmed on the quote.

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Video & edge analytics

E-core host with four L4 cards

Four 24 GB L4 cards handle video analytics and light inference while two 144-core Xeon 6780E processors run the surrounding container workload — 288 cores in the node. Sixteen 64 GB RDIMMs give 1 TB, and four E3.S drives hold the working set.

2 × Xeon 6780E — 144 cores @ 2.2 GHz, 330 W each
4 × NVIDIA L4 24 GB
16 × 64 GB DDR5-6400 RDIMM — 1 TB, one per channel
4 × 7.68 TB E3.S NVMe in one 4EDSFF cage
NS204i-u v2 boot device in the front cage
Broadcom BCM57414 2 × 10/25 GbE SFP28 PCIe
M-CRPS Titanium supplies — count confirmed for L4 cards (set on the quote)
Red Hat Enterprise Linux 9
HPE Tech Care Basic

HPE’s supply rule is written for double-wide GPU counts and the QuickSpecs print no width for the L4, so the supply count is confirmed at quote. E-core processors take DIMMs in totals of 4, 8, 16 or 32 and cannot use the 16 GB module.

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10 — Full specifications

HPE ProLiant Compute DL380a Gen12 specifications

Chassis & cooling

Form factor	4U rack · one 10DW (double-wide GPU) chassis type
CTO models	P76706-B21 (8 Double Wide/16 Single-Wide, iLO 7) · P74461-B21 (8DW, iLO 6)
Dimensions (H × W × D)	17.47 × 44.78 × 80.26 cm
Weight	37.5 kg minimum · 62.5 kg maximum (10DW front fan assembly) · 67.36 kg packaged
Fans	4 hot-plug assemblies (4 × 92 mm + 8 × 40 mm)
Liquid cooling	Optional CPU DLC kit P82520-B21 · occupies PCIe slot 1
Rails	Ball Bearing Rail Kit P69770-B21 · CMA P28726-B21 separate

Processor

Sockets	Two, same model (no single-processor build)
Family	Intel Xeon 6 — 6700E E-core, 6500P/6700P P-core
Cores per processor	8 to 144
TDP	150 W to 350 W
Listed SKUs	32 in the feature table · 31 option kits

Memory

Slots	32 DDR5 RDIMM · 16 per processor · 8 channels × 2 DPC
Kits	16, 32, 64, 96, 128 GB RDIMM · 256 GB 3DS RDIMM — all DDR5-6400
Speed	6400 MT/s (1 DPC) · 5200 MT/s (2 DPC), capped by the processor
Maximum	8.0 TB (32 × 256 GB) · 4.0 TB at 1 DPC

Storage

Front	4 or 8 × U.3 NVMe (4SFF cages) · 4, 8 or 16 × E3.S (4EDSFF cages; 16 per HPE’s storage table, while the cage kit lists a maximum of 2 cages)
Maximum (HPE table)	122.88 TB (8 × 15.36 TB U.3) · 245.76 TB (16 × 15.36 TB E3.S)
Controllers	Intel VROC (licensed) · MR416i-p, MR416i-o, MR932i-p
Boot	NS204i-u v2 480 GB, 960 GB or 960 GB SED — front cage

Accelerators

Listed	RTX PRO 6000 Blackwell 96 GB · RTX PRO 6000D 84 GB · H200 NVL 141 GB · L40S 48 GB · L20 48 GB · L4 24 GB
Counts	0, 1, 2, 4, 8 or 10 · RTX PRO 6000 max 8 · no mixing
NVLink	2-way / 4-way bridges · H200 NVL only · not in 10DW
Cabling	One 16-pin kit per 2 double-wide GPUs (P74700-B21 / P83526-B21)

Expansion & networking

PCIe	6 × PCIe 5.0 x16 FHHL · slots 3 and 6 by default
OCP	2 × OCP 3.0 (A and B) via cable kits
LAN	None embedded
DPU	BlueField B3220 or B3140H · max 1
Front NIC	Up to 4 cards in the 8DW NIC configuration

Power

Supplies	M-CRPS hot-plug · 2400 W and 3200 W Titanium · 2800 W 277 VAC Titanium
Count	5 for 2 or 4 double-wide GPUs · 8 for 8 or 10
Cords	C19/C19-C20 for the 2400 W and 3200 W units

Ports & video

Front	USB 3.2 Gen1 · iLO service port
Rear	2 × USB 3.2 Gen1 · VGA · 1 Gb iLO port · serial via IX port kit
Internal	1 × USB 3.2 Gen1
Video	1920 × 1200 at 60 Hz · 16 MB

Environment & warranty

Operating temperature	10–35 °C · 5–10 °C, 35–40 °C and 40–45 °C extended for approved configurations
Maximum altitude	3,050 m
Warranty	3 years parts, labour and onsite, next business day

11 — FAQ

DL380a Gen12 questions, answered from the documentation

How many GPUs does the HPE ProLiant Compute DL380a Gen12 hold?

Up to ten double-wide GPUs in its 4U chassis, in allowed counts of 0, 1, 2, 4, 8 or 10. The RTX PRO 6000 Blackwell stops at eight, models cannot be mixed, and eight or ten double-wide cards need two switchboard enablement kits and eight power supplies.

Which GPUs can the DL380a Gen12 take?

HPE lists the NVIDIA RTX PRO 6000 Blackwell Server Edition 96 GB, RTX PRO 6000D 84 GB, H200 NVL 141 GB, L40S 48 GB, L20 48 GB and L4 24 GB. Only the H200 NVL can use HPE’s 2-way and 4-way NVLink bridges. The QuickSpecs give no per-card power or width, so cooling and supply sizing are confirmed build by build.

What is the maximum memory of the DL380a Gen12?

8 TB, with all 32 slots holding 256 GB 3DS RDIMMs at 5200 MT/s. At one DIMM per channel the ceiling is 4 TB (16 × 256 GB) at 6400 MT/s. HPE also recommends twice the installed GPU memory in system RAM.

Which processors does the DL380a Gen12 support?

Two identical Intel Xeon 6 processors — one of the six 6700E E-core models (64–144 cores) or one of 26 P-core models (8–86 cores), rated 150 W to 350 W. P-core parts are not offered on the iLO 6 CTO model, and HPE’s warranty covers the 6776P only as an AI host processor.

How many drives does the DL380a Gen12 hold?

Four U.3 NVMe drives in the default 4SFF cage, eight with two cages, or E3.S NVMe in 4EDSFF cages. HPE’s storage table and two controller and cable options describe sixteen E3.S drives in four cages, while the cage kit lists a maximum of two, or eight drives. There are no SAS, SATA or LFF options.

How many power supplies does the DL380a Gen12 need?

Five M-CRPS supplies with two or four double-wide GPUs — two for the system board, three for the GPUs — and eight with eight or ten. The choices are 2400 W and 3200 W Titanium and a 2800 W 277 VAC unit; models cannot be mixed, and H200 NVL or RTX PRO 6000 builds need 2400 W or 3200 W.

What separates the two DL380a Gen12 CTO models?

P76706-B21 (8 Double Wide/16 Single-Wide) carries iLO 7 and takes every listed option. P74461-B21 (8DW) has iLO 6, cannot be upgraded to iLO 7, and excludes P-core processors, the RTX PRO 6000, the 10DW and 8DW NIC modes, the tri-mode controllers and a set of NICs and HBAs.

How big and heavy is the DL380a Gen12?

HPE lists it at 17.47 × 44.78 × 80.26 cm (height, width, depth), and gives a minimum weight of 37.5 kg and a maximum of 62.5 kg with the front fan assembly used for ten-GPU builds, or 67.36 kg packaged with rails, cable arm and cords.

How does the DL380a Gen12 differ from the DL380a Gen11?

By the two QuickSpecs, the Gen11 is a 2U server for four double-wide or eight single-wide GPUs, with 4th or 5th Gen Xeon Scalable, 24 DIMM slots to 3 TB, iLO 6 and Flex Slot supplies. The Gen12 moves to 4U and up to ten double-wide GPUs, with Xeon 6, 32 slots to 8 TB, iLO 7 on its main CTO model and M-CRPS supplies.

Is the HPE ProLiant Compute DL380a Gen12 end of life?

HPE’s QuickSpecs, at version 20 of 8 September 2026, do not state an end-of-sale or end-of-support date for this server, and its change log marks only options obsolete — Omni-Path and InfiniBand adapters among them. Our end-of-life checker will list dates if HPE publishes them.

Sources & verification

Where these figures come from

HPE ProLiant Compute DL380a Gen12 QuickSpecs (Version 20 - 08-Sep-2026) — Overview and chassis type; processor table and option kits; iLO by CTO model; memory and population rules; riser, OCP and I/O expansion kits; maximum internal storage, drive cages, storage cables and controllers; GPU options, NVLink and cable rules; M-CRPS supplies and counts; cooling options; technical specifications; Summary of Changes.
HPE ProLiant DL380a Gen11 QuickSpecs (Version 34 - August 3, 2026) — Gen11 form factor, GPU counts, processors, memory, iLO and supplies in the generation FAQ.

Specifications are extracted from HPE’s published documents and independently re-checked line by line. Configurations are quote-based; availability and exact options are confirmed at quotation. Last reviewed 2026-09-11.

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The DL380a Gen12 at a glance

Strengths

Watch-outs

32 supported processors, mapped

Processor landscape — cores × TDP

Processor explorer

32 DIMM slots, 16 per processor

Capacity with every slot filled

Operating speed

2 drive-cage kits, up to 16 bays

Headline layouts

Controllers & boot

Every documented drive-cage kit

GPUs, PCIe and networking

NVIDIA RTX PRO 6000 Blackwell Server Edition 96GB PCIe Accelerator for HPE

NVIDIA RTX PRO 6000D 84GB PCIe Accelerator for HPE

NVIDIA H200 NVL 141GB PCIe Accelerator for HPE

NVIDIA L40S 48GB PCIe Accelerator

NVIDIA L20 48GB PCIe GPU Accelerator for HPE

NVIDIA L4 24GB PCIe Accelerator for HPE

I/O topology

Network adapters HPE lists

3 power supplies, 2,400–3,200 W

Run it, secure it, choose the OS

Management

Security

Operating systems

How the DL380a Gen12 compares with its family

Four builds that suit the DL380a Gen12

Eight H200 NVL with NVLink

Eight RTX PRO 6000 Blackwell

Ten L40S in the 10DW layout

E-core host with four L4 cards

HPE ProLiant Compute DL380a Gen12 specifications

Chassis & cooling

Processor

Memory

Storage

Accelerators

Expansion & networking

Power

Ports & video

Environment & warranty

DL380a Gen12 questions, answered from the documentation

Where these figures come from

Buy & configure

Size the GPU build

Family & platform

Power, cooling & support

Get a quote for the HPE ProLiant Compute DL380a Gen12

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