HPE DL380a Gen12 vs Lenovo SR685a V3
A specification-by-specification comparison of the HPE ProLiant Compute DL380a Gen12 and the Lenovo ThinkSystem SR685a V3, built from HPE’s and Lenovo’s own documents. 5 headline measures favour the DL380a Gen12 and none favour the SR685a V3, and they share no processors.
Bottom line. DL380a Gen12 leads on virtualisation, databases and in-memory work, storage density, AI and acceleration. Neither vendor publishes benchmarks for these machines, so every call here is made on what their documents state.

The measures that decide it
Each row is a figure both vendors publish. Bars show the split between the two; a badge marks the larger figure, which is not always the better buy — a shallower chassis or a lower power ceiling can matter more.
Which one, and why
Drawn from the measures above and each model’s own data sheet. Neither vendor publishes benchmark results for these servers, so nothing here claims one is “faster”.
Choose the DL380a Gen12 if…
- Cores, fully populated: 288 against 256 on the SR685a V3
- Memory ceiling: 8 TB against 3 TB on the SR685a V3
- Accelerators: Up to 10 against Up to 8 on the SR685a V3
- Ten double-wide GPU positions in 4U, with the H200 NVL, RTX PRO 6000 Blackwell, RTX PRO 6000D, L40S, L20 and L4 in HPE’s accelerator list.
Choose the SR685a V3 if…
- One chassis, two GPU ecosystems: eight AMD MI300X OAM GPUs (192 GB HBM3, 5.3 TB/s, 750 W each) or eight NVIDIA H200 SXM5 GPUs (141 GB, listed as HBM3e in the GPU table, 4.8 TB/s, 700 W each).
Where each one pulls ahead
Calls made on documented capacity only — cores, memory, bays, accelerators and network options — with the figures behind each one shown.
Side by side, differences first
Everything both documents state, grouped. The default view hides rows where the two machines are identical.
Processors
Every processor each vendor lists for the model, from its own document.
| Specification | DL380a Gen12 | SR685a V3 |
|---|---|---|
| Processors listed | 32 | 12 |
| Most cores per processor | 144 | 128 |
| Highest processor TDP | 350 W | 400 W |
| Processor families | Xeon 6 E-core · Xeon 6 P-core | AMD EPYC 9005 · AMD EPYC 9004 |
Memory
| Specification | DL380a Gen12 | SR685a V3 |
|---|---|---|
| DIMM slots | 32 | 24 |
| Slots per processor | 16 | 12 |
| Largest module listed | 256 GB | 128 GB |
| Memory types | RDIMM DDR5-6400 | RDIMM DDR5-6400 (5th Gen, operates 6000) · 10x4 RDIMM / RDIMM DDR5-4800 (4th Gen) · 3DS RDIMM |
Storage
Bay counts are the maximum each document states, including rear and mid-chassis positions.
| Specification | DL380a Gen12 | SR685a V3 |
|---|---|---|
| Documented layouts | 2 | 1 |
| Bay sizes | 2.5-inch · E3.S | 2.5-inch |
| Boot devices | HPE NS204i-u v2 960GB NVMe Hot Plug Boot Optimized Storage Device · HPE NS204i-u v2 960GB NVMe SED Hot Plug Boot Optimized Storage Device · HPE NS204i-u v2 480GB NVMe Hot Plug Boot Optimized Storage Device + 1 more | ThinkSystem M.2 NVMe 2-Bay RAID Adapter (B8P9) - Marvell 88NR2241 RAID-0/1, PCIe 3.0 x2, no SED; no field upgrade |
| Storage controllers | 7 | 2 |
Accelerators & I/O
| Specification | DL380a Gen12 | SR685a V3 |
|---|---|---|
| Accelerators supported | Up to 10 | Up to 8 |
| OCP slots | 2 | 1 |
| PCIe network slots | 6 | 10 |
| Network cards listed | 36 | 12 |
Power & platform
| Specification | DL380a Gen12 | SR685a V3 |
|---|---|---|
| Power-supply options | 3 | 1 |
| Output range | 2,400–3,200 W | 2,600–2,600 W |
| Input types | AC · 277 VAC / HVDC | AC |
| Management | HPE iLO 7 | XClarity Controller 2 |
| Chassis depthVendors measure depth differently — see each data sheet | 80.26 cm (31.60 in) deep | 924 mm |
Processors, memory, bays and power
The same charts each data sheet carries, drawn to the same scale so the two ranges can be read against each other.
DL380a Gen12: processors by cores and TDP
SR685a V3: processors by cores and TDP
DL380a Gen12: memory with every slot filled
SR685a V3: memory with every slot filled
DL380a Gen12: drive bays
Front panel
4 × 2.5" NVMe at the front — 4 bays in total.
SR685a V3: drive bays
Front panel
8 × 2.5" NVMe at the front — 8 bays in total.
DL380a Gen12: power supplies
SR685a V3: power supplies
DL380a Gen12 vs SR685a V3, answered
Is the DL380a Gen12 or the SR685a V3 the faster server?
Neither document publishes benchmark results, so this page compares what they do state. The DL380a Gen12 lists 32 processors up to 144 cores at 350 W; the SR685a V3 lists 12 up to 128 cores at 400 W. Fully populated that is 288 cores against 256.
Which holds more memory?
The DL380a Gen12 has 32 DIMM slots and a stated ceiling of 8.0 TB. The SR685a V3 has 24 and 3 TB.
Which takes more drives?
DL380a Gen12: 16 bays across 2 documented layouts. SR685a V3: 16 across 1. Counts include rear and mid-chassis positions where the vendor documents them.
Can either take GPUs?
DL380a Gen12: up to 10 accelerators, 0 double-wide cards listed. SR685a V3: up to 8, 0 double-wide listed.
Do they share any processors?
No. The two documents list different processors, so a like-for-like processor build is not possible across these two.
Where these figures come from. DL380a Gen12: HPE ProLiant Compute DL380a Gen12 QuickSpecs (Version 20 - 08-Sep-2026) (HPE document). SR685a V3: Lenovo ThinkSystem SR685a V3 Server Product Guide (July 15, 2026) (Lenovo document). Each claim on this page is derived from those documents, checked page by page on the two data sheets, and carries no pricing.
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