HPE DL380 Gen11 vs Lenovo SR650a V4
A specification-by-specification comparison of the HPE ProLiant DL380 Gen11 and the Lenovo ThinkSystem SR650a V4, built from HPE’s and Lenovo’s own documents. 1 headline measure favours the DL380 Gen11, 3 favour the SR650a V4, and they share no processors.
Bottom line. DL380 Gen11 leads on storage density. SR650a V4 leads on virtualisation, network throughput. Neither vendor publishes benchmarks for these machines, so every call here is made on what their documents state.

The measures that decide it
Each row is a figure both vendors publish. Bars show the split between the two; a badge marks the larger figure, which is not always the better buy — a shallower chassis or a lower power ceiling can matter more.
Which one, and why
Drawn from the measures above and each model’s own data sheet. Neither vendor publishes benchmark results for these servers, so nothing here claims one is “faster”.
Choose the DL380 Gen11 if…
- Drive bays: 36 against 8 on the SR650a V4
- Five factory chassis — 8SFF, 24SFF, 8LFF, 12LFF and 12EDSFF — plus mid-tray and rear cages, so one model spans small SFF builds, 16 LFF bays and 36 EDSFF NVMe drives.
Choose the SR650a V4 if…
- Cores, fully populated: 172 against 128 on the DL380 Gen11
- Largest power supply: 3,200 W against 2,200 W on the DL380 Gen11
- Fastest network option: 800 GbE class against 400 GbE class on the DL380 Gen11
- One 2U chassis spans eight low-profile L4 cards, four double-wide cards of up to 450 W, or a pair of 600 W H200 NVL or RTX PRO 6000 Blackwell GPUs, all in PCIe 5.0 front slots.
Where each one pulls ahead
Calls made on documented capacity only — cores, memory, bays, accelerators and network options — with the figures behind each one shown.
Side by side, differences first
Everything both documents state, grouped. The default view hides rows where the two machines are identical.
Processors
Every processor each vendor lists for the model, from its own document.
| Specification | DL380 Gen11 | SR650a V4 |
|---|---|---|
| Processors listed | 66 | 27 |
| Most cores per processor | 64 | 86 |
| Highest processor TDP | 385 W | 350 W |
| Processor families | 5th Gen Xeon Scalable · 4th Gen Xeon Scalable | Xeon 6 P-core |
Memory
| Specification | DL380 Gen11 | SR650a V4 |
|---|---|---|
| Fastest rated speed | 5,600 MT/s | 8,800 MT/s |
| Memory types | RDIMM DDR5-5600 · RDIMM DDR5-4800 · RDIMM 3DS DDR5-5600 · RDIMM 3DS DDR5-4800 | RDIMM DDR5-6400 · 3DS RDIMM DDR5-6400 · MRDIMM DDR5-8800 (operates at 8000) |
Storage
Bay counts are the maximum each document states, including rear and mid-chassis positions.
| Specification | DL380 Gen11 | SR650a V4 |
|---|---|---|
| Maximum bays | 36 | 8 |
| Documented layouts | 13 | 4 |
| Bay sizes | 2.5-inch · 3.5-inch · E3.S | 2.5-inch · E3.S |
| Boot devices | HPE NS204i-u Gen11 NVMe Hot Plug Boot Optimized Storage Device · HPE NS204i-u v2 960GB NVMe Hot Plug Boot Optimized Storage Device · HPE NS204i-u v2 960GB NVMe SED Hot Plug Boot Optimized Storage Device + 2 more | ThinkSystem M.2 RAID B550i-2i SATA/NVMe Enablement Kit (internal, 2x M.2 NVMe, integrated Broadcom RAID) · ThinkSystem M.2 RAID B545i-2i SATA/NVMe Adapter (internal, 2x M.2 SATA/NVMe, integrated Broadcom RAID) · ThinkSystem M.2 B350i-2i NVMe Enablement Kit (internal, 2x M.2 NVMe x2, VROC RAID) + 4 more |
| Storage controllers | 13 | 24 |
Accelerators & I/O
| Specification | DL380 Gen11 | SR650a V4 |
|---|---|---|
| Double-wide cards listed | 3 | 4 |
| PCIe network slots | 8 | 14 |
| Network cards listed | 39 | 31 |
Power & platform
| Specification | DL380 Gen11 | SR650a V4 |
|---|---|---|
| Power-supply options | 5 | 14 |
| Output range | 800–2,200 W | 800–3,200 W |
| Input types | AC · −48 V DC | AC · 277 VAC / HVDC · −48 V DC |
| Management | HPE iLO 6 | XClarity Controller 3 |
| Chassis depthVendors measure depth differently — see each data sheet | SFF CTO: 72.7 cm (28.62 in) | 924 mm (36.4 in.) |
Processors, memory, bays and power
The same charts each data sheet carries, drawn to the same scale so the two ranges can be read against each other.
DL380 Gen11: processors by cores and TDP
SR650a V4: processors by cores and TDP
DL380 Gen11: memory with every slot filled
SR650a V4: memory with every slot filled
DL380 Gen11: drive bays
Front panel
12 × EDSFF NVMe at the front — 12 bays in total.
SR650a V4: drive bays
Front panel
8 × 2.5" NVMe at the front — 8 bays in total.
DL380 Gen11: power supplies
SR650a V4: power supplies
DL380 Gen11 vs SR650a V4, answered
Is the DL380 Gen11 or the SR650a V4 the faster server?
Neither document publishes benchmark results, so this page compares what they do state. The DL380 Gen11 lists 66 processors up to 64 cores at 385 W; the SR650a V4 lists 27 up to 86 cores at 350 W. Fully populated that is 128 cores against 172.
Which holds more memory?
The DL380 Gen11 has 32 DIMM slots and a stated ceiling of 8.0 TB. The SR650a V4 has 32 and 8 TB.
Which takes more drives?
DL380 Gen11: 36 bays across 13 documented layouts. SR650a V4: 8 across 4. Counts include rear and mid-chassis positions where the vendor documents them.
Can either take GPUs?
DL380 Gen11: up to 8 accelerators, 3 double-wide cards listed. SR650a V4: up to 8, 4 double-wide listed.
Do they share any processors?
No. The two documents list different processors, so a like-for-like processor build is not possible across these two.
Where these figures come from. DL380 Gen11: HPE ProLiant DL380 Gen11 QuickSpecs (Version 47 - 08-Sep-2026) (HPE document). SR650a V4: Lenovo ThinkSystem SR650a V4 and SR650i V4 Servers (August 27, 2026) (Lenovo document). Each claim on this page is derived from those documents, checked page by page on the two data sheets, and carries no pricing.
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