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Head-to-head · every figure from the vendor documents

HPE DL380 Gen12 vs Lenovo SR650a V4

A specification-by-specification comparison of the HPE ProLiant Compute DL380 Gen12 and the Lenovo ThinkSystem SR650a V4, built from HPE’s and Lenovo’s own documents. 2 headline measures favour the DL380 Gen12, 2 favour the SR650a V4, and 21 processors appear in both lists.

Bottom line. DL380 Gen12 leads on virtualisation, storage density. SR650a V4 leads on network throughput. Neither vendor publishes benchmarks for these machines, so every call here is made on what their documents state.

HPE ProLiant Compute DL380 Gen12 2U server, front view: 24 SFF bays in three 8-bay boxes, USB-C iLO port, USB port and health LEDs
HPE ProLiant
DL380 Gen12
2U Rack2 sockets32 DIMMHPE iLO 7
Configure the DL380 Gen12 →Full data sheet
VS
Lenovo ThinkSystem SR650a V4 front view: eight 2.5-inch hot-swap drive bays in the centre between the perforated covers of the front GPU slots
Lenovo ThinkSystem
SR650a V4
2U Rack2 sockets32 DIMMXClarity Controller 3
Configure the SR650a V4 →Full data sheet
01 — Scoreboard

The measures that decide it

Each row is a figure both vendors publish. Bars show the split between the two; a badge marks the larger figure, which is not always the better buy — a shallower chassis or a lower power ceiling can matter more.

2
Processor sockets
2
288Higher
Cores, fully populated
Largest listed processor × its socket count
172
8 TB
Memory ceiling
As each document states it
8 TB
36Higher
Drive bays
8
Up to 8
Accelerators
Up to 8
2,200 W
Largest power supply
Higher3,200 W
2U Rack
Rack height
2U Rack
400 GbE class
Fastest network option
Higher800 GbE class
02 — Verdict

Which one, and why

Drawn from the measures above and each model’s own data sheet. Neither vendor publishes benchmark results for these servers, so nothing here claims one is “faster”.

Choose the DL380 Gen12 if…

  • Cores, fully populated: 288 against 172 on the SR650a V4
  • Drive bays: 36 against 8 on the SR650a V4
  • Two Xeon 6 core types in one chassis: seven E-core parts of 64 to 144 cores for dense throughput, and 27 P-core parts of 8 to 86 cores for per-core speed.

Choose the SR650a V4 if…

  • Largest power supply: 3,200 W against 2,200 W on the DL380 Gen12
  • Fastest network option: 800 GbE class against 400 GbE class on the DL380 Gen12
  • One 2U chassis spans eight low-profile L4 cards, four double-wide cards of up to 450 W, or a pair of 600 W H200 NVL or RTX PRO 6000 Blackwell GPUs, all in PCIe 5.0 front slots.
03 — By workload

Where each one pulls ahead

Calls made on documented capacity only — cores, memory, bays, accelerators and network options — with the figures behind each one shown.

VirtualisationDL380 Gen12: 288 cores with 8 TB. SR650a V4: 172 cores with 8 TB.DL380 Gen12
Databases & in-memoryMemory ceiling 8 TB against 8 TB, across 32 and 32 DIMM slots.Line ball
Storage density36 bays in 2U against 8 in 2U.DL380 Gen12
AI & acceleration8 accelerators against 8 in the vendor documents.Line ball
Network throughputFastest card listed: 400 GbE class against 800 GbE class.SR650a V4
04 — Specifications

Side by side, differences first

Everything both documents state, grouped. The default view hides rows where the two machines are identical.

Processors

Every processor each vendor lists for the model, from its own document.

SpecificationDL380 Gen12SR650a V4
Processors listed3427
Most cores per processor14486
Processor familiesXeon 6 E-core · Xeon 6 P-coreXeon 6 P-core

Memory

SpecificationDL380 Gen12SR650a V4
Fastest rated speed6,400 MT/s8,800 MT/s
Memory typesRDIMM DDR5-6400RDIMM DDR5-6400 · 3DS RDIMM DDR5-6400 · MRDIMM DDR5-8800 (operates at 8000)

Storage

Bay counts are the maximum each document states, including rear and mid-chassis positions.

SpecificationDL380 Gen12SR650a V4
Maximum bays368
Documented layouts134
Bay sizes2.5-inch · E3.S · 3.5-inch2.5-inch · E3.S
Boot devicesHPE NS204i-u v2 480GB NVMe Hot Plug Boot Optimized Storage Device · HPE NS204i-u v2 960GB NVMe Hot Plug Boot Optimized Storage Device · HPE NS204i-u v2 960GB NVMe SED Hot Plug Boot Optimized Storage Device + 3 moreThinkSystem M.2 RAID B550i-2i SATA/NVMe Enablement Kit (internal, 2x M.2 NVMe, integrated Broadcom RAID) · ThinkSystem M.2 RAID B545i-2i SATA/NVMe Adapter (internal, 2x M.2 SATA/NVMe, integrated Broadcom RAID) · ThinkSystem M.2 B350i-2i NVMe Enablement Kit (internal, 2x M.2 NVMe x2, VROC RAID) + 4 more
Storage controllers1423

Accelerators & I/O

SpecificationDL380 Gen12SR650a V4
PCIe network slots814
Network cards listed3931

Power & platform

SpecificationDL380 Gen12SR650a V4
Power-supply options514
Output range800–2,200 W800–3,200 W
Input typesAC · −48 V DCAC · 277 VAC / HVDC · −48 V DC
ManagementHPE iLO 7XClarity Controller 3
Chassis depthVendors measure depth differently — see each data sheetSFF/EDSFF CTO: 72.70 cm (28.62 in)924 mm (36.4 in.)
05 — The data

Processors, memory, bays and power

The same charts each data sheet carries, drawn to the same scale so the two ranges can be read against each other.

DL380 Gen12: processors by cores and TDP

HPE ProLiant Compute DL380 Gen12 processors081624324048566472808896104112120128136144100 W150 W200 W250 W300 W350 WCores per processorIntel Xeon 6780E — 144 cores · 330 W · 2.2 GHz base · 108 MB cache · DDR5-6400Intel Xeon 6766E — 144 cores · 250 W · 1.9 GHz base · 108 MB cache · DDR5-6400Intel Xeon 6756E — 128 cores · 225 W · 1.8 GHz base · 96 MB cache · DDR5-6400Intel Xeon 6746E — 112 cores · 250 W · 2 GHz base · 96 MB cache · DDR5-5600Intel Xeon 6731E — 96 cores · 250 W · 2.2 GHz base · 96 MB cache · DDR5-5600Intel Xeon 6740E — 96 cores · 250 W · 2.4 GHz base · 96 MB cache · DDR5-6400Intel Xeon 6710E — 64 cores · 205 W · 2.4 GHz base · 96 MB cache · DDR5-5600Intel Xeon 6787P — 86 cores · 350 W · 2 GHz base · 336 MB cache · DDR5-6400Intel Xeon 6788P — 86 cores · 350 W · 2 GHz base · 336 MB cache · DDR5-6400Intel Xeon 6762P — 64 cores · 350 W · 2.9 GHz base · 320 MB cache · DDR5-6400Intel Xeon 6767P — 64 cores · 350 W · 2.4 GHz base · 336 MB cache · DDR5-6400Intel Xeon 6760P — 64 cores · 330 W · 2.2 GHz base · 320 MB cache · DDR5-6400Intel Xeon 6768P — 64 cores · 330 W · 2.4 GHz base · 336 MB cache · DDR5-6400Intel Xeon 6747P — 48 cores · 330 W · 2.7 GHz base · 288 MB cache · DDR5-6400Intel Xeon 6748P — 48 cores · 300 W · 2.5 GHz base · 192 MB cache · DDR5-6400Intel Xeon 6740P — 48 cores · 270 W · 2.1 GHz base · 288 MB cache · DDR5-6400Intel Xeon 6736P — 36 cores · 205 W · 2 GHz base · 144 MB cache · DDR5-6400Intel Xeon 6732P — 32 cores · 350 W · 3.8 GHz base · 144 MB cache · DDR5-6400Intel Xeon 6745P — 32 cores · 300 W · 3.1 GHz base · 336 MB cache · DDR5-6400Intel Xeon 6737P — 32 cores · 270 W · 2.9 GHz base · 144 MB cache · DDR5-6400Intel Xeon 6738P — 32 cores · 270 W · 2.9 GHz base · 144 MB cache · DDR5-6400Intel Xeon 6730P — 32 cores · 250 W · 2.5 GHz base · 288 MB cache · DDR5-6400Intel Xeon 6530P — 32 cores · 225 W · 2.3 GHz base · 144 MB cache · DDR5-6400Intel Xeon 6527P — 24 cores · 255 W · 3 GHz base · 144 MB cache · DDR5-6400Intel Xeon 6520P — 24 cores · 210 W · 2.4 GHz base · 144 MB cache · DDR5-6400Intel Xeon 6728P — 24 cores · 210 W · 2.7 GHz base · 144 MB cache · DDR5-6400Intel Xeon 6725P — 16 cores · 235 W · 3.7 GHz base · 192 MB cache · DDR5-6400Intel Xeon 6724P — 16 cores · 210 W · 3.6 GHz base · 72 MB cache · DDR5-6400Intel Xeon 6517P — 16 cores · 190 W · 3.2 GHz base · 72 MB cache · DDR5-6400Intel Xeon 6515P — 16 cores · 150 W · 2.3 GHz base · 72 MB cache · DDR5-6400Intel Xeon 6505P — 12 cores · 150 W · 2.2 GHz base · 48 MB cache · DDR5-6400Intel Xeon 6714P — 8 cores · 165 W · 4 GHz base · 48 MB cache · DDR5-6400Intel Xeon 6507P — 8 cores · 150 W · 3.5 GHz base · 48 MB cache · DDR5-6400Intel Xeon 6503P — 8 cores · 135 W · 2.8 GHz base · 48 MB cache · DDR5-64006780E144 cores — the top SKU6766E1.7 W/core — most efficient
Xeon 6 E-core 7Xeon 6 P-core 27Bubble size = L3 cache · hover a bubble for the full SKU

SR650a V4: processors by cores and TDP

Lenovo ThinkSystem SR650a V4 processors0816243240485664728088100 W150 W200 W250 W300 W350 WCores per processorIntel Xeon 6 6787P — 86 cores / 172 threads · 350 W · 2 GHz base · 336 MB cache · DDR5-6400Intel Xeon 6 6781P — 80 cores / 160 threads · 350 W · 2 GHz base · 336 MB cache · DDR5-6400Intel Xeon 6 6761P — 64 cores / 128 threads · 350 W · 2.5 GHz base · 336 MB cache · DDR5-6400Intel Xeon 6 6767P — 64 cores / 128 threads · 350 W · 2.4 GHz base · 336 MB cache · DDR5-6400Intel Xeon 6 6760P — 64 cores / 128 threads · 330 W · 2.2 GHz base · 320 MB cache · DDR5-6400Intel Xeon 6 6747P — 48 cores / 96 threads · 330 W · 2.7 GHz base · 288 MB cache · DDR5-6400Intel Xeon 6 6741P — 48 cores / 96 threads · 300 W · 2.5 GHz base · 288 MB cache · DDR5-6400Intel Xeon 6 6740P — 48 cores / 96 threads · 270 W · 2.1 GHz base · 288 MB cache · DDR5-6400Intel Xeon 6 6736P — 36 cores / 72 threads · 205 W · 2 GHz base · 144 MB cache · DDR5-6400Intel Xeon 6 6732P — 32 cores / 64 threads · 350 W · 3.8 GHz base · 144 MB cache · DDR5-6400Intel Xeon 6 6745P — 32 cores / 64 threads · 300 W · 3.1 GHz base · 336 MB cache · DDR5-6400Intel Xeon 6 6737P — 32 cores / 64 threads · 270 W · 2.9 GHz base · 144 MB cache · DDR5-6400Intel Xeon 6 6730P — 32 cores / 64 threads · 250 W · 2.5 GHz base · 288 MB cache · DDR5-6400Intel Xeon 6 6731P — 32 cores / 64 threads · 245 W · 2.5 GHz base · 144 MB cache · DDR5-6400Intel Xeon 6 6530P — 32 cores / 64 threads · 225 W · 2.3 GHz base · 144 MB cache · DDR5-6400Intel Xeon 6 6527P — 24 cores / 48 threads · 255 W · 3 GHz base · 144 MB cache · DDR5-6400Intel Xeon 6 6521P — 24 cores / 48 threads · 225 W · 2.6 GHz base · 144 MB cache · DDR5-6400Intel Xeon 6 6520P — 24 cores / 48 threads · 210 W · 2.4 GHz base · 144 MB cache · DDR5-6400Intel Xeon 6 6725P — 16 cores / 32 threads · 235 W · 3.7 GHz base · 192 MB cache · DDR5-6400Intel Xeon 6 6724P — 16 cores / 32 threads · 210 W · 3.6 GHz base · 72 MB cache · DDR5-6400Intel Xeon 6 6517P — 16 cores / 32 threads · 190 W · 3.2 GHz base · 72 MB cache · DDR5-6400Intel Xeon 6 6511P — 16 cores / 32 threads · 150 W · 2.3 GHz base · 72 MB cache · DDR5-6400Intel Xeon 6 6515P — 16 cores / 32 threads · 150 W · 2.3 GHz base · 72 MB cache · DDR5-6400Intel Xeon 6 6505P — 12 cores / 24 threads · 150 W · 2.2 GHz base · 48 MB cache · DDR5-6400Intel Xeon 6 6714P — 8 cores / 16 threads · 165 W · 4 GHz base · 48 MB cache · DDR5-6400Intel Xeon 6 6507P — 8 cores / 16 threads · 150 W · 3.5 GHz base · 48 MB cache · DDR5-6400Intel Xeon 6 6503P — 8 cores / 16 threads · 135 W · 2.8 GHz base · 48 MB cache · DDR5-64006 6787P86 cores · 4.1 W/core — top SKU and most efficient
Xeon 6 P-core 27Bubble size = L3 cache · hover a bubble for the full SKU

DL380 Gen12: memory with every slot filled

16 GB512 GB32 GB1 TB64 GB2 TB96 GB3 TB128 GB4 TB256 GB8 TB32 slots · 16 per processor · each tick = one DIMM

SR650a V4: memory with every slot filled

16 GB512 GB32 GB1 TB64 GB2 TB96 GB3 TB128 GB4 TB256 GB8 TB32 slots · 16 per processor · each tick = one DIMM

DL380 Gen12: drive bays

Front panel

12 × EDSFF NVMe at the front — 12 bays in total.

SAS/SATANVMeSAS/SATA + NVMe

SR650a V4: drive bays

Front panel

8 × 2.5" NVMe at the front — 8 bays in total.

SAS/SATANVMeSAS/SATA + NVMe

DL380 Gen12: power supplies

05001000150020002500800 W Platinum — HPE 800W Flex Slot Platinum Hot Plug Low Halogen Power Supply Kit. Input voltage not printed. Not compatible with Energy Star 4.0 compliance (doc: 'Platinum Power Supply 800W & 1600W are not compatible').800Platinum1000 W Titanium — HPE 1000W Flex Slot Titanium Hot Plug Power Supply Kit. Named in the ErP Lot 9 section as 96% efficient. Input voltage not printed.1000Titanium1600 W null — HPE 1600W Flex Slot -48VDC Hot Plug Power Supply Kit; no efficiency rating printed. Requires HPE 1600W -48VDC Power Cable Lug Kit (P36877-B21) OR the 1600W DC PSU Power Cable Kit.1600DC1600 W Platinum — HPE 1600W Flex Slot Platinum Hot Plug Low Halogen Power Supply Kit. '1600W Power supplies only support high line voltage (200 VAC to 240 VAC).' Not compatible with Energy Star 4.0 compliance.1600Platinum2200 W Titanium — Printed as 'HPE 1800W-2200W Flex Slot Titanium Hot Plug Power Supply Kit' (watts recorded as upper figure; per-voltage ratings not printed). Named in the ErP Lot 9 section as 96% efficient.2200TitaniumWatts · dashed line = output at 100–120 V low line
AC−48 V DC

SR650a V4: power supplies

0500100015002000250030003500800 W Platinum — CRPS v1.5; 230V/115V; C14800Platinum800 W Titanium — CRPS Premium; 230V/115V; C14800Titanium800 W Titanium — CRPS v1.4; 230V/115V; C14800Titanium1300 W not stated — -48V DC CRPS Premium (-44V to -54V DC); BizLink connector; efficiency rating not stated in doc1300DC1300 W Platinum — CRPS v1.5; 230V/115V (1000W at 115V); C141300Platinum1300 W Platinum — CRPS v2.4; 230V/115V (1000W at 115V); C141300Platinum1300 W Platinum — HVAC/HVDC CRPS Premium; 200-277V AC / 240-380V DC; Amphenol connector1300Platinum1300 W Titanium — CRPS Premium; 230V/115V (1000W at 115V); C141300Titanium1300 W Titanium — CRPS v2.4; 230V/115V (1000W at 115V); C141300Titanium2000 W Titanium — CRPS Premium; 230V only; C142000Titanium2700 W Platinum — CRPS v2.3; 230V only; C202700Platinum2700 W Platinum — CRPS v2.4; 230V only; C202700Platinum2700 W Titanium — CRPS Premium; 230V only; C202700Titanium3200 W Titanium — CRPS Premium; 230V only; C203200TitaniumWatts · dashed line = output at 100–120 V low line
AC277 VAC / HVDC−48 V DC
06 — Like for like

21 processors you can order in either

Both vendor documents list these parts, so a build can be matched across the two and the comparison comes down to the chassis: 13 more are exclusive to the DL380 Gen12 and 6 to the SR650a V4.

ProcessorCoresTDP
Intel Xeon 6787P86350 W
Intel Xeon 6767P64350 W
Intel Xeon 6760P64330 W
Intel Xeon 6747P48330 W
Intel Xeon 6740P48270 W
Intel Xeon 6736P36205 W
Intel Xeon 6730P32250 W
Intel Xeon 6732P32350 W
Intel Xeon 6737P32270 W
Intel Xeon 6745P32300 W
Intel Xeon 6530P32225 W
Intel Xeon 6527P24255 W
07 — Questions

DL380 Gen12 vs SR650a V4, answered

Is the DL380 Gen12 or the SR650a V4 the faster server?

Neither document publishes benchmark results, so this page compares what they do state. The DL380 Gen12 lists 34 processors up to 144 cores at 350 W; the SR650a V4 lists 27 up to 86 cores at 350 W. Fully populated that is 288 cores against 172.

Which holds more memory?

The DL380 Gen12 has 32 DIMM slots and a stated ceiling of 8.0 TB. The SR650a V4 has 32 and 8 TB.

Which takes more drives?

DL380 Gen12: 36 bays across 13 documented layouts. SR650a V4: 8 across 4. Counts include rear and mid-chassis positions where the vendor documents them.

Can either take GPUs?

DL380 Gen12: up to 8 accelerators, 4 double-wide cards listed. SR650a V4: up to 8, 4 double-wide listed.

Do they share any processors?

Yes — 21 processors appear in both documents, including the Intel Xeon 6787P. That makes a like-for-like build possible on either server.

Where these figures come from. DL380 Gen12: HPE ProLiant DL380 Gen12 QuickSpecs (Version 19 - 08-Sep-2026) (HPE document). SR650a V4: Lenovo ThinkSystem SR650a V4 and SR650i V4 Servers (August 27, 2026) (Lenovo document). Each claim on this page is derived from those documents, checked page by page on the two data sheets, and carries no pricing.

Other comparisons in this class

R7625 vs DL380 Gen12Dell vs HPER770 vs DL380 Gen12Dell vs HPER7725 vs DL380 Gen12Dell vs HPEDL380 Gen11 vs SR650a V4HPE vs LenovoDL380 Gen12 vs SR665 V3HPE vs LenovoDL380a Gen11 vs SR650a V4HPE vs LenovoR760 vs SR650a V4Dell vs LenovoDL380 Gen11 vs DL380 Gen12Generation upgrade

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