Dell R7625 vs HPE DL380 Gen12
A specification-by-specification comparison of the Dell PowerEdge R7625 and the HPE ProLiant Compute DL380 Gen12, built from Dell’s and HPE’s own documents. 1 headline measure favours the R7625, 4 favour the DL380 Gen12, and they share no processors.
Bottom line. DL380 Gen12 leads on virtualisation, databases and in-memory work, AI and acceleration, network throughput. Neither vendor publishes benchmarks for these machines, so every call here is made on what their documents state.
The measures that decide it
Each row is a figure both vendors publish. Bars show the split between the two; a badge marks the larger figure, which is not always the better buy — a shallower chassis or a lower power ceiling can matter more.
Which one, and why
Drawn from the measures above and each model’s own data sheet. Neither vendor publishes benchmark results for these servers, so nothing here claims one is “faster”.
Choose the R7625 if…
- Largest power supply: 3,200 W against 2,200 W on the DL380 Gen12
- Two sockets and 24 DDR5 slots in 2U, for up to 256 cores and 6 TB — twice the memory of the one-socket R7615 in the same chassis height.
Choose the DL380 Gen12 if…
- Cores, fully populated: 288 against 256 on the R7625
- Memory ceiling: 8 TB against 6 TB on the R7625
- Accelerators: Up to 8 against Up to 6 on the R7625
- Two Xeon 6 core types in one chassis: seven E-core parts of 64 to 144 cores for dense throughput, and 27 P-core parts of 8 to 86 cores for per-core speed.
Where each one pulls ahead
Calls made on documented capacity only — cores, memory, bays, accelerators and network options — with the figures behind each one shown.
Side by side, differences first
Everything both documents state, grouped. The default view hides rows where the two machines are identical.
Processors
Every processor each vendor lists for the model, from its own document.
| Specification | R7625 | DL380 Gen12 |
|---|---|---|
| Processors listed | 19 | 34 |
| Most cores per processor | 128 | 144 |
| Highest processor TDP | 400 W | 350 W |
| Processor families | AMD EPYC 9004 | Xeon 6 E-core · Xeon 6 P-core |
Memory
| Specification | R7625 | DL380 Gen12 |
|---|---|---|
| DIMM slots | 24 | 32 |
| Slots per processor | 12 | 16 |
| Memory types | RDIMM DDR5-4800 · RDIMM DDR5-5600 · RDIMM DDR5-6400 | RDIMM DDR5-6400 |
Storage
Bay counts are the maximum each document states, including rear and mid-chassis positions.
| Specification | R7625 | DL380 Gen12 |
|---|---|---|
| Documented layouts | 23 | 13 |
| Bay sizes | 3.5-inch · 2.5-inch · E3.S | 2.5-inch · E3.S · 3.5-inch |
| Boot devices | BOSS-N1 · IDSDM | HPE NS204i-u v2 480GB NVMe Hot Plug Boot Optimized Storage Device · HPE NS204i-u v2 960GB NVMe Hot Plug Boot Optimized Storage Device · HPE NS204i-u v2 960GB NVMe SED Hot Plug Boot Optimized Storage Device + 3 more |
| Storage controllers | 10 | 14 |
Accelerators & I/O
| Specification | R7625 | DL380 Gen12 |
|---|---|---|
| Accelerators supported | Up to 6 | Up to 8 |
| Double-wide cards listed | 0 | 4 |
| OCP slots | 1 | 2 |
| Network cards listed | 16 | 39 |
Power & platform
| Specification | R7625 | DL380 Gen12 |
|---|---|---|
| Power-supply options | 10 | 5 |
| Output range | 800–3,200 W | 800–2,200 W |
| Input types | AC · 277 VAC / HVDC · −48 V DC | AC · −48 V DC |
| Management | iDRAC9 | HPE iLO 7 |
| Chassis depthVendors measure depth differently — see each data sheet | 772.13 mm with bezel / 758.29 mm without bezel | SFF/EDSFF CTO: 72.70 cm (28.62 in) |
Processors, memory, bays and power
The same charts each data sheet carries, drawn to the same scale so the two ranges can be read against each other.
R7625: processors by cores and TDP
DL380 Gen12: processors by cores and TDP
R7625: memory with every slot filled
DL380 Gen12: memory with every slot filled
R7625: drive bays
Front panel
Rear module
32 × EDSFF NVMe at the front, plus 4 × EDSFF SAS/SATA at the rear — 36 bays in total.
DL380 Gen12: drive bays
Front panel
12 × EDSFF NVMe at the front — 12 bays in total.
R7625: power supplies
DL380 Gen12: power supplies
R7625 vs DL380 Gen12, answered
Is the R7625 or the DL380 Gen12 the faster server?
Neither document publishes benchmark results, so this page compares what they do state. The R7625 lists 19 processors up to 128 cores at 400 W; the DL380 Gen12 lists 34 up to 144 cores at 350 W. Fully populated that is 256 cores against 288.
Which holds more memory?
The R7625 has 24 DIMM slots and a stated ceiling of 6 TB. The DL380 Gen12 has 32 and 8.0 TB.
Which takes more drives?
R7625: 36 bays across 23 documented layouts. DL380 Gen12: 36 across 13. Counts include rear and mid-chassis positions where the vendor documents them.
Can either take GPUs?
R7625: up to 6 accelerators, 0 double-wide cards listed. DL380 Gen12: up to 8, 4 double-wide listed.
Do they share any processors?
No. The two documents list different processors, so a like-for-like processor build is not possible across these two.
Where these figures come from. R7625: Dell PowerEdge R7625 Technical Guide (July 2026, Rev. A07) (Dell document). DL380 Gen12: HPE ProLiant DL380 Gen12 QuickSpecs (Version 19 - 08-Sep-2026) (HPE document). Each claim on this page is derived from those documents, checked page by page on the two data sheets, and carries no pricing.
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